Computational identification and characterization of chitinase 1 and chitinase 2 from neotropical isolates of Beauveria bassiana

Chitinases 1 and 2 demonstrated variations, especially within chitinase 1, which presented a potential paralog. These differences were observed in their physical parameters. Additionally, CHIT2 completely lacks a signal peptide. This implies that CHIT1 might be associated with infection processes, while CHIT2 could be involved in morphogenesis and cellular growth. Therefore, our work highlights the importance of computational studies on local isolates, providing valuable resources for further experimental validation. Intrinsic changes within local species can significantly impact our understanding of complex pathogen-host interactions and offer practical applications, such as biological control.

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Publication Details

Journal
Frontiers in Bioinformatics
Published
2024-10-18
DOI
https://doi.org/10.3389/fbinf.2024.1434442
Citations
4
Primary Topic
Studies on Chitinases and Chitosanases
Type
article
Field-Weighted Citation Impact
0.94
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article

Computational identification and characterization of chitinase 1 and chitinase 2 from neotropical isolates of Beauveria bassiana

Ramón Molina‐Bravo, Allan González-Herrera, Stefany Solano-González, Juan Segura-Vega
4 citations
Frontiers in Bioinformatics
Studies on Chitinases and Chitosanases
0.94
article

Computational identification and characterization of chitinase 1 and chitinase 2 from neotropical isolates of Beauveria bassiana

Ramón Molina‐Bravo, Allan González-Herrera, Stefany Solano-González, Juan Segura-Vega
article en
4 citations

Abstract

Chitinases 1 and 2 demonstrated variations, especially within chitinase 1, which presented a potential paralog. These differences were observed in their physical parameters. Additionally, CHIT2 completely lacks a signal peptide. This implies that CHIT1 might be associated with infection processes, while CHIT2 could be involved in morphogenesis and cellular growth. Therefore, our work highlights the importance of computational studies on local isolates, providing valuable resources for further experimental validation. Intrinsic changes within local species can significantly impact our understanding of complex pathogen-host interactions and offer practical applications, such as biological control.

Frontiers in BioinformaticsVol. 4
Universidad Nacional (CR)
Life in Land
Openalex Percentile: Top 25%
Studies on Chitinases and Chitosanases
0.94
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