Computational identification and characterization of chitinase 1 and chitinase 2 from neotropical isolates of Beauveria bassiana
Chitinases 1 and 2 demonstrated variations, especially within chitinase 1, which presented a potential paralog. These differences were observed in their physical parameters. Additionally, CHIT2 completely lacks a signal peptide. This implies that CHIT1 might be associated with infection processes, while CHIT2 could be involved in morphogenesis and cellular growth. Therefore, our work highlights the importance of computational studies on local isolates, providing valuable resources for further experimental validation. Intrinsic changes within local species can significantly impact our understanding of complex pathogen-host interactions and offer practical applications, such as biological control.
Authors
- Ramón Molina‐Bravo (ORCID: https://orcid.org/0000-0001-5564-4426)
- Allan González-Herrera (ORCID: https://orcid.org/0000-0002-6571-1036)
- Stefany Solano-González (ORCID: https://orcid.org/0000-0002-1167-2174)
- Juan Segura-Vega
Institutions
- Universidad Nacional (CR)
Publication Details
- Journal
- Frontiers in Bioinformatics
- Published
- 2024-10-18
- DOI
- https://doi.org/10.3389/fbinf.2024.1434442
- Citations
- 4
- Primary Topic
- Studies on Chitinases and Chitosanases
- Type
- article
- Field-Weighted Citation Impact
- 0.94