Perspectives of Diabetes Mellitus on Vital Organ

The study investigates the association between type 2 diabetes mellitus and liver function in 50 diabetic individuals compared to 30 controls, predominantly males. Liver function tests, including ALT, AST, ALP, serum albumin, and bilirubin, were conducted. Diabetic individuals were categorized into four grades based on fasting blood sugar levels. Compared to controls, diabetic individuals exhibited lower levels of total serum proteins, albumin, and albumin to globulin ratio, with grade IV diabetes showing particularly notable deviations, including low total serum proteins and albumin levels, alongside elevated thymol turbidity and alkaline phosphatase. However, individuals with lower-grade diabetes did not display significant alterations in liver function. This study underscores the importance of monitoring liver function, especially in advanced stages of type 2 diabetes, for timely intervention and management.

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Publication Details

Journal
International Journal of Medical Science
Published
2024-08-31
DOI
https://doi.org/10.14445/23939117/ijms-v11i4p104
Primary Topic
Diet and metabolism studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Perspectives of Diabetes Mellitus on Vital Organ

Dev Brat Mishra, Prashant Kumar Singh, Sandhya Pandey, Divya Mishra et al.
International Journal of Medical Science
Diet and metabolism studies
article

Perspectives of Diabetes Mellitus on Vital Organ

Dev Brat Mishra, Prashant Kumar Singh, Sandhya Pandey, Divya Mishra, Sankalp Yadav
article en

Abstract

The study investigates the association between type 2 diabetes mellitus and liver function in 50 diabetic individuals compared to 30 controls, predominantly males. Liver function tests, including ALT, AST, ALP, serum albumin, and bilirubin, were conducted. Diabetic individuals were categorized into four grades based on fasting blood sugar levels. Compared to controls, diabetic individuals exhibited lower levels of total serum proteins, albumin, and albumin to globulin ratio, with grade IV diabetes showing particularly notable deviations, including low total serum proteins and albumin levels, alongside elevated thymol turbidity and alkaline phosphatase. However, individuals with lower-grade diabetes did not display significant alterations in liver function. This study underscores the importance of monitoring liver function, especially in advanced stages of type 2 diabetes, for timely intervention and management.

International Journal of Medical ScienceVol. 11(4)
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Diet and metabolism studies
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Perspectives of Diabetes Mellitus on Vital Organ — Dev Brat Mishra, Prashant Kumar Singh, et al. · International Journal of Medical Science (2024) | TGRS Research Map | TGRS