Time-dependent simulation of blood flow through an abdominal aorta with iliac arteries

Atherosclerosis is one of the important diseases of the circulatory system because atherosclerotic plaques cause significant disruption of blood flow. Therefore, it is very important to properly understand these processes and skillfully simulate blood flow. In our work, we consider blood flow through an abdominal aorta with iliac arteries, assuming that the right iliac artery is narrowed by an atherosclerotic lesion. Blood flow is simulated using the laminar, standard <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:mrow><mml:mi>k</mml:mi> <mml:mo>-</mml:mo> <mml:mi>ω</mml:mi></mml:mrow> </mml:math> and standard <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:mrow><mml:mi>k</mml:mi> <mml:mo>-</mml:mo> <mml:mi>ϵ</mml:mi></mml:mrow> </mml:math> models. The obtained results show that despite the use of identical initial conditions, the distribution of velocity flow and wall shear stress depends on the choice of flow simulation model. For the <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:mrow><mml:mi>k</mml:mi> <mml:mo>-</mml:mo> <mml:mi>ϵ</mml:mi></mml:mrow> </mml:math> model, we obtain higher values of speed and wall shear stress on atherosclerotic plaque than in the other two models. The laminar and <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:mrow><mml:mi>k</mml:mi> <mml:mo>-</mml:mo> <mml:mi>ω</mml:mi></mml:mrow> </mml:math> models predict larger areas where reverse blood flow occurs in the area behind the atherosclerotic lesion. This effect is associated with negative wall shear stress. These two models give very similar results. The results obtained by us, and those reported in the literature, indicate that <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:mrow><mml:mi>k</mml:mi> <mml:mo>-</mml:mo> <mml:mi>ω</mml:mi></mml:mrow> </mml:math> model is the most suitable for blood flow analysis.

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Publication Details

Journal
European Biophysics Journal
Published
2024-10-18
DOI
https://doi.org/10.1007/s00249-024-01724-w
Citations
5
Primary Topic
Coronary Interventions and Diagnostics
Type
article
Field-Weighted Citation Impact
2.86
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article

Time-dependent simulation of blood flow through an abdominal aorta with iliac arteries

Grzegorz Górski, Krzysztof Kucab
5 citations
European Biophysics Journal
Coronary Interventions and Diagnostics
2.86
article

Time-dependent simulation of blood flow through an abdominal aorta with iliac arteries

Grzegorz Górski, Krzysztof Kucab
article en
5 citations

Abstract

Atherosclerosis is one of the important diseases of the circulatory system because atherosclerotic plaques cause significant disruption of blood flow. Therefore, it is very important to properly understand these processes and skillfully simulate blood flow. In our work, we consider blood flow through an abdominal aorta with iliac arteries, assuming that the right iliac artery is narrowed by an atherosclerotic lesion. Blood flow is simulated using the laminar, standard <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:mrow><mml:mi>k</mml:mi> <mml:mo>-</mml:mo> <mml:mi>ω</mml:mi></mml:mrow> </mml:math> and standard <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:mrow><mml:mi>k</mml:mi> <mml:mo>-</mml:mo> <mml:mi>ϵ</mml:mi></mml:mrow> </mml:math> models. The obtained results show that despite the use of identical initial conditions, the distribution of velocity flow and wall shear stress depends on the choice of flow simulation model. For the <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:mrow><mml:mi>k</mml:mi> <mml:mo>-</mml:mo> <mml:mi>ϵ</mml:mi></mml:mrow> </mml:math> model, we obtain higher values of speed and wall shear stress on atherosclerotic plaque than in the other two models. The laminar and <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:mrow><mml:mi>k</mml:mi> <mml:mo>-</mml:mo> <mml:mi>ω</mml:mi></mml:mrow> </mml:math> models predict larger areas where reverse blood flow occurs in the area behind the atherosclerotic lesion. This effect is associated with negative wall shear stress. These two models give very similar results. The results obtained by us, and those reported in the literature, indicate that <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:mrow><mml:mi>k</mml:mi> <mml:mo>-</mml:mo> <mml:mi>ω</mml:mi></mml:mrow> </mml:math> model is the most suitable for blood flow analysis.

European Biophysics JournalVol. 53(7-8)
Institute of Physics (PL), University of Rzeszów (PL)
Openalex Percentile: Top 9%
Coronary Interventions and Diagnostics
2.86
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