Targeting Leishmaniasis with Nitrovinyl Derivatives: Synthesis, In Vitro Assessment, and Computational Exploration
In vitro evaluations and computational analyses strongly suggest that these compounds could be effective against both L. major amastigotes and promastigotes. Additionally, they exhibited notable synergistic interactions with MA against both living forms of the parasite.
Authors
- Ehsan Faghih‐Mirzaei (ORCID: https://orcid.org/0000-0001-5109-2644)
- Mohammad Amin Langarizadeh (ORCID: https://orcid.org/0000-0002-1344-1222)
- Ehsan Salarkia (ORCID: https://orcid.org/0000-0001-6125-5101)
- Ali Asadipour (ORCID: https://orcid.org/0000-0002-1449-2195)
- Marziye Ranjbar Tavakoli
- Yaghoub Pourshojaei (ORCID: https://orcid.org/0000-0002-6994-7361)
- Mehdi Ranjbar (ORCID: https://orcid.org/0000-0002-5844-3299)
- Bagher Amirheidari (ORCID: https://orcid.org/0000-0003-1086-4286)
- Fatemeh Ghelich Khani
- Fatemeh Sharifi (ORCID: https://orcid.org/0000-0003-4701-6926)
Institutions
- Kerman University of Medical Sciences (IR)
Publication Details
- Journal
- Current Medicinal Chemistry
- Published
- 2024-10-18
- DOI
- https://doi.org/10.2174/0109298673323271241002060614
- Citations
- 2
- Primary Topic
- Research on Leishmaniasis Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.09