Limosilactobacillus-related 3-OMDP as a potential therapeutic target for depression
These results indicated that gut microbiota might affect host's inflammation levels in brain through regulating neurotransmitters, eventually leading to the onset of depression. 'Limosilactobacillus-3-OMDP-IL-1β/IL-6' might be a potential pathway in the crosstalk of gut and brain, and 3-OMDP held the promise as a therapeutic target for depression.
Authors
- Yi Ren (ORCID: https://orcid.org/0000-0003-1560-5531)
- Jianjun Chen
- Wentao Wu (ORCID: https://orcid.org/0000-0001-9516-577X)
- Qi Zhong (ORCID: https://orcid.org/0000-0002-8489-3461)
- Peng Xie (ORCID: https://orcid.org/0000-0002-0081-6048)
- Jing Xie
- Ke Xu (ORCID: https://orcid.org/0000-0001-7222-9523)
- Jiaolin Wang
Institutions
- Chongqing University (CN)
- The Affiliated Yongchuan Hospital of Chongqing Medical University (CN)
- Chongqing Emergency Medical Center (CN)
- Chongqing Medical University (CN)
Publication Details
- Journal
- Annals of Medicine
- Published
- 2024-10-18
- DOI
- https://doi.org/10.1080/07853890.2024.2417179
- Citations
- 5
- Primary Topic
- Tryptophan and brain disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.79
Funders
- Chongqing Postdoctoral Science Foundation
- National Natural Science Foundation of China
- China Postdoctoral Science Foundation
- Chongqing Medical University
- Chongqing Municipal Education Commission
- National Key Research and Development Program of China