The Key Role of Wettability and Boundary Layer in Dissolution Rate Test
The proposed mathematical model confirms the importance of the different physical phenomena leading the dissolution of poly-disperse solid drug particles in a solution. Although a comprehensive mathematical model was proposed and applied, the DRT data of theophylline and praziquantel was successfully fitted by means of just two fitting parameters.
Authors
- Dario Voinovich (ORCID: https://orcid.org/0000-0003-3830-8038)
- Angelo Cortesi (ORCID: https://orcid.org/0000-0003-2227-7935)
- Gabriele Grassi (ORCID: https://orcid.org/0000-0001-9704-6651)
- Erica Franceschinis (ORCID: https://orcid.org/0000-0002-3915-5144)
- Michela Abrami (ORCID: https://orcid.org/0000-0002-9785-3741)
- Mario Grassi (ORCID: https://orcid.org/0000-0002-3532-3200)
- Gesmi Milcovich (ORCID: https://orcid.org/0000-0003-0096-6668)
- Alice Biasin (ORCID: https://orcid.org/0000-0003-2841-1277)
- Lucia Grassi
- Italo Colombo
- Federico Pribac
Institutions
- University of Modena and Reggio Emilia (IT)
- University of Padua (IT)
- University of Trieste (IT)
- Ospedale di Cattinara (IT)
- University of Palermo (IT)
Publication Details
- Journal
- Pharmaceutics
- Published
- 2024-10-18
- DOI
- https://doi.org/10.3390/pharmaceutics16101335
- Citations
- 1
- Primary Topic
- Drug Solubulity and Delivery Systems
- Type
- article
- Field-Weighted Citation Impact
- 0.21