LiTMP-LiBr complex-induced lateral lithiation and cross ester condensation: direct access to isocoumarins from 2-methoxy <i>o</i>-toluate esters
LiTMP-LiBr complex promotes cross-ester coupling of 2-methoxy o -toluate esters to directly yield isocoumarin is demonstrated. Method applied to many natural product precursors including synthesis of (+)- and (−)-lunatinins.
Authors
- Goreti Rajendar (ORCID: https://orcid.org/0000-0003-3742-319X)
- Mintu Rehman (ORCID: https://orcid.org/0000-0001-8913-3958)
- D. Sajib
- Rasajna Madhusudhana
Institutions
- Indian Institute of Science Education and Research Thiruvananthapuram (IN)
Publication Details
- Journal
- Organic Chemistry Frontiers
- Published
- 2024-10-18
- DOI
- https://doi.org/10.1039/d4qo01678e
- Citations
- 1
- Primary Topic
- Synthesis and Biological Activity
- Type
- article
- Field-Weighted Citation Impact
- 0.29
Funders
- Indian Institute of Science Education and Research Mohali