Comparative evaluation of autologous tissue-engineered ocular and oral mucosal tissue grafts- a prospective randomized controlled trial
Both cell types are effective to restore the ocular surface integrity in bilateral ocular surface disease. Whereas COMET is safe and efficacious in terms of improvement of clinical parameters including, BCVA, corneal clarity, reduction in vascularization and preventing the recurrence of symblepharon postoperatively 3months and 6 months. In addition, the CCET group maintained the stability of the ocular surface and had improvement in corneal clarity and a decrease in vascularization at 3 months compared to their pre-operative characteristics.
Authors
- Neiwete Lomi (ORCID: https://orcid.org/0000-0002-8071-2440)
- Murugesan Vanathi (ORCID: https://orcid.org/0000-0002-3643-4260)
- Amit Kumar Das (ORCID: https://orcid.org/0000-0001-9703-1898)
- Seema Sen (ORCID: https://orcid.org/0000-0001-5408-2353)
- Sujata Mohanty (ORCID: https://orcid.org/0000-0002-0047-4914)
- Radhika Tandon (ORCID: https://orcid.org/0000-0001-9554-9933)
- Mani Kalaivani (ORCID: https://orcid.org/0000-0002-6492-1808)
- Seema Kashyap (ORCID: https://orcid.org/0000-0002-8746-9017)
- Misba Majood (ORCID: https://orcid.org/0000-0003-4219-1389)
- Pranav Kumar Pandey
- Noopur Gupta (ORCID: https://orcid.org/0000-0001-8022-6656)
- Tanveer Alam Khan
Institutions
- Institute of Medical Sciences (IN)
- All India Institute of Medical Sciences (IN)
Publication Details
- Journal
- BMC Biotechnology
- Published
- 2024-10-18
- DOI
- https://doi.org/10.1186/s12896-024-00876-z
- Citations
- 1
- Primary Topic
- Corneal Surgery and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.40
Funders
- Department of Biotechnology, Ministry of Science and Technology, India