Detection of circulating tumor cells in patients with lung cancer using a rare cell sorter: a pilot study
The ability of the RCS to detect CTCs in patients with lung cancer was demonstrated based on the concordance of EGFR status in this pilot study. This novel hybrid method of CTC recovery using the RCS has the potential to recover a wide range of CTCs regardless of EpCAM. Further validation through a large-scale study is needed.
Authors
- Atsuko Furukawa
- Yukinobu Goto (ORCID: https://orcid.org/0000-0003-0348-973X)
- Shinji Kikuchi (ORCID: https://orcid.org/0000-0002-6776-7463)
- Taisuke Masuda (ORCID: https://orcid.org/0000-0002-7853-9511)
- Bilal Turan (ORCID: https://orcid.org/0000-0003-1183-5268)
- Kazuto Sugai (ORCID: https://orcid.org/0000-0002-5639-7663)
- Naohiro Kobayashi (ORCID: https://orcid.org/0000-0002-1663-8039)
- Hideo Ichimura (ORCID: https://orcid.org/0000-0002-2779-0108)
- Tomoko Mori (ORCID: https://orcid.org/0000-0001-8308-7890)
- Fumihito Arai (ORCID: https://orcid.org/0000-0002-2508-1615)
- Yukio Sato (ORCID: https://orcid.org/0000-0002-0041-6159)
- Satoshi Matsusaka
- Yasuharu Sekine
Institutions
- University of Tsukuba (JP)
- Ibaraki Prefectural Central Hospital (JP)
- The University of Tokyo (JP)
Publication Details
- Journal
- BMC Cancer
- Published
- 2024-10-18
- DOI
- https://doi.org/10.1186/s12885-024-12945-9
- Citations
- 3
- Primary Topic
- Cancer Cells and Metastasis
- Type
- article
- Field-Weighted Citation Impact
- 0.85
Funders
- Japan Agency for Medical Research and Development
- Japan Society for the Promotion of Science