Intravascular Lithotripsy for Peripheral Artery Calcification: 30-Day Outcomes From the Disrupt PAD III Observational Study

The Disrupt PAD III OS represents the largest assessment of IVL periprocedural outcomes in calcified PAD. It confirmed excellent procedural safety and effectiveness in complex lesions across multiple peripheral vascular beds.Clinical ImpactThis final analysis of the PAD III OS represents the largest report of peripheral IVL utilization in daily clinical practice. The outcomes of this study indicate that previously reported procedural results in clinical trial settings can be translated to a broader patient population. Treatment with peripheral IVL in severely calcified stenotic lower limb lesions demonstrated consistent acute safety and stenosis reduction, even in complex patients across multiple vessel beds. In addition, the importance of proper IVL balloon sizing to achieve excellent acute stenosis reduction was confirmed by multivariate analysis.

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Publication Details

Journal
Journal of Endovascular Therapy
Published
2024-10-18
DOI
https://doi.org/10.1177/15266028241283716
Citations
6
Primary Topic
Peripheral Artery Disease Management
Type
article
Field-Weighted Citation Impact
3.44
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article

Intravascular Lithotripsy for Peripheral Artery Calcification: 30-Day Outcomes From the Disrupt PAD III Observational Study

Barry Bertolet, Gunnar Tepe, William A. Gray, Sahil A. Parikh et al.
6 citations
Journal of Endovascular Therapy
Peripheral Artery Disease Management
3.44
article

Intravascular Lithotripsy for Peripheral Artery Calcification: 30-Day Outcomes From the Disrupt PAD III Observational Study

Barry Bertolet, Gunnar Tepe, William A. Gray, Sahil A. Parikh, Nicolas W. Shammas, Anderson Mehrle, Sarang Mangalmurti, Ehrin J. Armstrong, Andrew Holden, George L. Adams, Peter Soukas, James F. McKinsey, Edward Y. Woo
article en
6 citations

Abstract

The Disrupt PAD III OS represents the largest assessment of IVL periprocedural outcomes in calcified PAD. It confirmed excellent procedural safety and effectiveness in complex lesions across multiple peripheral vascular beds.Clinical ImpactThis final analysis of the PAD III OS represents the largest report of peripheral IVL utilization in daily clinical practice. The outcomes of this study indicate that previously reported procedural results in clinical trial settings can be translated to a broader patient population. Treatment with peripheral IVL in severely calcified stenotic lower limb lesions demonstrated consistent acute safety and stenosis reduction, even in complex patients across multiple vessel beds. In addition, the importance of proper IVL balloon sizing to achieve excellent acute stenosis reduction was confirmed by multivariate analysis.

Journal of Endovascular TherapyVol. 33(2)
MedStar Washington Hospital Center (US), Mount Sinai Health System (US), Providence College (US), Bryn Mawr Hospital (US), Auckland City Hospital (NZ), Rex Hospital (US), Phillips 66 (United States) (US), Lankenau Heart Institute (US), Midwest Cardiovascular Research Foundation (US), RoMed Kliniken (DE), Lifespan (US), North Mississippi Medical Center (US), Columbia University (US), University of Colorado Denver (US)
Good health and well-being
Openalex Percentile: Top 7%
Peripheral Artery Disease Management
3.44
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