Circulating RAC1 contributed to steroid-sensitive nephrotic syndrome: Mendelian randomization, single-cell RNA-sequencing, proteomic, and experimental evidence
Increased expression of <i>RAC1</i> might be causally associated with SSNS, suggesting that targeting RAC1 might represent a potential therapeutic strategy for SSNS.
Authors
- Yi Wang (ORCID: https://orcid.org/0000-0002-0818-724X)
- Tianwen Yao (ORCID: https://orcid.org/0000-0003-1379-8835)
- Shisheng Han (ORCID: https://orcid.org/0009-0003-5131-8668)
- Yi Zhang (ORCID: https://orcid.org/0000-0003-0859-9735)
- Yanqiu Xu (ORCID: https://orcid.org/0000-0002-2201-4361)
Institutions
- Shanghai University of Traditional Chinese Medicine (CN)
- Yueyang Hospital (CN)
Publication Details
- Journal
- Renal Failure
- Published
- 2024-10-18
- DOI
- https://doi.org/10.1080/0886022x.2024.2416087
- Primary Topic
- Renal Diseases and Glomerulopathies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China