Improving the Diagnostic Accuracy of RECAM in North American Patients With Suspected Idiosyncratic Drug-Induced Liver Injury
Among 120 suspected DILI cases, RUCAM had better agreement with DILIN expert opinion scores vs RECAM. Making HCV RNA and anti-HEV IgM testing optional significantly improved agreement between RECAM and DILIN expert opinion. Future modifications to RECAM are needed to improve causality assessment in North American patients with suspected DILI.
Authors
- Jeremy Louissaint (ORCID: https://orcid.org/0000-0003-1154-1825)
- David G. Goldfarb (ORCID: https://orcid.org/0000-0003-2682-7543)
- Adam Myer
- Kenneth E. Sherman (ORCID: https://orcid.org/0000-0002-0560-0019)
- Robert J. Fontana (ORCID: https://orcid.org/0000-0001-9161-5892)
- Jacob Ciricillo (ORCID: https://orcid.org/0000-0002-8462-5176)
- Askanda Osman
- Yeshika Sharma
- Amoah Yeboah‐Korang (ORCID: https://orcid.org/0000-0001-9283-3349)
- Farrah Rahim
Institutions
- Albert Einstein College of Medicine (US)
- Harvard University (US)
- University of Michigan (US)
- Massachusetts General Hospital (US)
- Michigan Medicine (US)
- University of Cincinnati (US)
- The University of Texas Southwestern Medical Center (US)
Publication Details
- Journal
- The American Journal of Gastroenterology
- Published
- 2024-10-18
- DOI
- https://doi.org/10.14309/ajg.0000000000003147
- Citations
- 5
- Primary Topic
- Drug-Induced Hepatotoxicity and Protection
- Type
- article
- Field-Weighted Citation Impact
- 2.33
Funders
- American Association for the Study of Liver Diseases