Spatiotemporal characteristics of eustachian tube development in <scp>C57BL</scp>/6 mice: Correlation between morphological and functional maturation
In C57BL/6 mice, E16.5 marks a critical period for middle ear cavity and ET formation. Muc5b plays a foundational role during early stages, while Muc5ac enhances function in later stages. During P7-11, despite morphological maturity, ET function remains underdeveloped but continues to improve with growth.
Authors
- Hongjun Xiao (ORCID: https://orcid.org/0000-0002-1776-5435)
- Hejie Li (ORCID: https://orcid.org/0000-0002-4851-7194)
- Xiang Shen (ORCID: https://orcid.org/0000-0002-9578-5845)
- Xiaoye Chen (ORCID: https://orcid.org/0009-0003-0615-5476)
- Shimin Zong (ORCID: https://orcid.org/0009-0004-3709-1599)
- Huimin Zhang (ORCID: https://orcid.org/0000-0002-4407-6723)
- Ting Li (ORCID: https://orcid.org/0009-0009-2967-3237)
- Xuan Yu (ORCID: https://orcid.org/0009-0009-9130-2939)
- Wenting Yu
Institutions
- Wuhan Union Hospital (CN)
- Huazhong University of Science and Technology (CN)
Publication Details
- Journal
- Developmental Dynamics
- Published
- 2024-10-18
- DOI
- https://doi.org/10.1002/dvdy.753
- Primary Topic
- Ear Surgery and Otitis Media
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China