Refinement of Hy Law Using the Drug-Induced Liver Injury Network Database

Initial R values were the most reliable means of identifying Hy Law cases. There were some drugs that caused HC injury with jaundice but with mortality rates < 10%. Refinement of Hy Law is warranted.

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Publication Details

Journal
The American Journal of Gastroenterology
Published
2024-10-18
DOI
https://doi.org/10.14309/ajg.0000000000003145
Citations
7
Primary Topic
Drug-Induced Hepatotoxicity and Protection
Type
article
Field-Weighted Citation Impact
3.27

Funders

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article

Refinement of Hy Law Using the Drug-Induced Liver Injury Network Database

Andrew Stolz, Huiman X. Barnhart, Paul Hideyo Hayashi, Jay H. Hoofnagle
7 citations
The American Journal of Gastroenterology
Drug-Induced Hepatotoxicity and Protection
3.27
article

Refinement of Hy Law Using the Drug-Induced Liver Injury Network Database

Andrew Stolz, Huiman X. Barnhart, Paul Hideyo Hayashi, Jay H. Hoofnagle
article en
7 citations

Abstract

Initial R values were the most reliable means of identifying Hy Law cases. There were some drugs that caused HC injury with jaundice but with mortality rates < 10%. Refinement of Hy Law is warranted.

The American Journal of GastroenterologyVol. 120(6)
University of North Carolina at Chapel Hill (US), Center for Drug Evaluation and Research (US), Duke University (US), Keck Hospital of USC (US), Clinical Research Institute (US), National Institute of Diabetes and Digestive and Kidney Diseases (US)
University of Southern California, Thomas Jefferson University, National Institutes of Health, National Cancer Institute, National Institute of Diabetes and Digestive and Kidney Diseases
Good health and well-being
Openalex Percentile: Top 8%
Drug-Induced Hepatotoxicity and Protection
3.27
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