Dietary Probiotic Pediococcus acidilactici GKA4, Dead Probiotic GKA4, and Postbiotic GKA4 Improves Cisplatin-Induced AKI by Autophagy and Endoplasmic Reticulum Stress and Organic Ion Transporters
Overall, the potential therapeutic benefits of GKA4, dead probiotic GKA4, and postbiotic GKA4 are significant, particularly after cisplatin treatment. This is achieved by modulating apoptosis, autophagy, ER stress, and transporter proteins to alleviate oxidative stress.
Authors
- Chin‐Chu Chen (ORCID: https://orcid.org/0000-0002-5340-6552)
- You‐Shan Tsai
- Jaung‐Geng Lin (ORCID: https://orcid.org/0000-0002-3642-8047)
- Yen‐Lien Chen (ORCID: https://orcid.org/0000-0002-0928-2724)
- Shih-Wei Lin (ORCID: https://orcid.org/0000-0003-1343-0838)
- Wen‐Ping Jiang (ORCID: https://orcid.org/0000-0001-9387-680X)
- Guan‐Jhong Huang (ORCID: https://orcid.org/0000-0002-9822-3485)
Institutions
- Shih Chien University (TW)
- Asia University (TW)
- Chung Yuan Christian University (TW)
- National Taiwan University (TW)
- China Medical University (TW)
- Grape King (Taiwan) (TW)
Publication Details
- Journal
- Nutrients
- Published
- 2024-10-18
- DOI
- https://doi.org/10.3390/nu16203532
- Citations
- 5
- Primary Topic
- Chemotherapy-induced organ toxicity mitigation
- Type
- article
- Field-Weighted Citation Impact
- 2.12
Funders
- China Medical University
- China Medical University, Taiwan