Osteopontin Promotes Cholangiocyte Secretion of Chemokines to Support Macrophage Recruitment and Fibrosis in <scp>MASH</scp>
OPN promotes cholangiocyte chemokine secretion and the accumulation of pro-inflammatory monocytes. These data support neutralisation of OPN as an anti-inflammatory and anti-fibrotic strategy.
Authors
- Ali Canbay (ORCID: https://orcid.org/0000-0001-6069-7899)
- Leo A. van Grunsven (ORCID: https://orcid.org/0000-0002-0990-7034)
- Manal F. Abdelmalek (ORCID: https://orcid.org/0000-0002-5001-8618)
- Marco A. Briones‐Orta (ORCID: https://orcid.org/0000-0001-6627-1901)
- Anna Mae Diehl (ORCID: https://orcid.org/0000-0003-1859-089X)
- Bertus Eksteen (ORCID: https://orcid.org/0000-0001-7165-9214)
- Svenja Sydor (ORCID: https://orcid.org/0000-0002-1349-8309)
- Danielle T. Vannan
- Jason D. Coombes (ORCID: https://orcid.org/0000-0002-5601-8977)
- Shilpa Chokshi (ORCID: https://orcid.org/0000-0003-1735-8538)
- Ayako Suzuki (ORCID: https://orcid.org/0000-0003-1824-1067)
- Naoto Kitamura (ORCID: https://orcid.org/0000-0002-1940-4609)
- Paul Manka (ORCID: https://orcid.org/0000-0001-8589-7280)
- Patricia Aspichueta (ORCID: https://orcid.org/0000-0002-3553-1755)
- Antonio Riva (ORCID: https://orcid.org/0000-0002-4974-2780)
- Salvatore Papa (ORCID: https://orcid.org/0000-0002-8369-6538)
- Cynthia A. Moylan (ORCID: https://orcid.org/0000-0001-8454-7086)
- Paul C. Kuo (ORCID: https://orcid.org/0000-0003-0904-8636)
- Marzena Swiderska‐Syn (ORCID: https://orcid.org/0000-0001-7364-0728)
- Zhiyong Mi
- Wing‐Kin Syn
- Lee C. Claridge
- Rasha Younis
- Shanna Bittencourt
Institutions
- University of Leeds (GB)
- Mayo Clinic (US)
- Vrije Universiteit Brussel (BE)
- University of Calgary (CA)
- University of the Basque Country (ES)
- Duke University (US)
- King's College London (GB)
- University of South Florida (US)
- Leeds Teaching Hospitals NHS Trust (GB)
- St James's University Hospital (GB)
- WinnMed (US)
- Foundation for Liver Research (GB)
- Saint Louis University (US)
Publication Details
- Journal
- Liver International
- Published
- 2024-10-18
- DOI
- https://doi.org/10.1111/liv.16131
- Citations
- 7
- Primary Topic
- Liver physiology and pathology
- Type
- article
- Field-Weighted Citation Impact
- 2.59
Funders
- Foundation for Liver Research
- Région de Bruxelles-Capitale
- Rosetrees Trust
- University of Birmingham
- Deutsche Forschungsgemeinschaft
- Belgian Federal Science Policy Office
- Bardham Research and Education Trust
- Alberta Innovates
- European Association for the Study of the Liver
- Guts UK
- National Institutes of Health
- Natural Sciences and Engineering Research Council of Canada