Inhibitor development upon switching from plasma-derived to recombinant factor VIII in previously untreated patients with severe hemophilia A: the PUP-SWITCH study
PUP-SWITCH, a study focusing on PUPs undergoing a product class switch from pdFVIII to rFVIII after 50 EDs, showed that switching appears to be safe pertaining to the risk of development of new inhibitors.
Authors
- Barış Yılmaz (ORCID: https://orcid.org/0000-0002-6542-0570)
- Amin Shahsavani (ORCID: https://orcid.org/0000-0002-4592-312X)
- Sinan Akbayram (ORCID: https://orcid.org/0000-0001-7410-4310)
- Canan Albayrak (ORCID: https://orcid.org/0000-0002-9912-9626)
- Mohsen Saleh Elalfy (ORCID: https://orcid.org/0000-0002-2809-1552)
- Frits R. Rosendaal (ORCID: https://orcid.org/0000-0003-2558-7496)
- Behnaz Habibpanah (ORCID: https://orcid.org/0000-0002-2738-2534)
- Susan Halimeh (ORCID: https://orcid.org/0000-0001-8596-9870)
- Gabriella Nicolò
- Zühre Kaya (ORCID: https://orcid.org/0000-0002-3798-7246)
- Mehran Karimi (ORCID: https://orcid.org/0000-0001-8555-1001)
- Nazan Sarper (ORCID: https://orcid.org/0000-0003-1599-774X)
- Flora Peyvandi (ORCID: https://orcid.org/0000-0001-7423-9864)
- Yılmaz Ay (ORCID: https://orcid.org/0000-0003-0397-6669)
- Dilek Gürlek Gökçebay (ORCID: https://orcid.org/0000-0001-8097-3950)
- Syna Miri (ORCID: https://orcid.org/0000-0002-6930-3099)
- Sara Scardo (ORCID: https://orcid.org/0009-0009-4539-545X)
- Ahmad Mohammadi (ORCID: https://orcid.org/0000-0003-3546-9653)
- Kaan Kavaklı (ORCID: https://orcid.org/0000-0002-4910-2142)
- Peyman Eshghi (ORCID: https://orcid.org/0000-0002-3503-1363)
- Tiraje Çelkan (ORCID: https://orcid.org/0000-0001-7287-1276)
- Namık Yaşar Özbek (ORCID: https://orcid.org/0000-0001-6857-0681)
- Soha Mohammadi Moghaddam
- Pier Mannuccio Mannucci
- Burçak Tatlı Güneş (ORCID: https://orcid.org/0009-0003-5478-8913)
Institutions
- Ain Shams University (EG)
- American University in Dubai (AE)
- University of Milan (IT)
- Shiraz University of Medical Sciences (IR)
- Ondokuz Mayıs University (TR)
- Leiden University Medical Center (NL)
- Dubai Hospital (AE)
- Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico (IT)
- Hemophilia Center of Iran (IR)
- Memorial Ankara Hospital (TR)
- Istanbul University-Cerrahpaşa (TR)
- Rhine-Ruhr Institute for Applied Systeminnovation (DE)
- Hemophilia Center of Western Pennsylvania (US)
- Izmir Tepecik Eğitim ve Araştırma Hastanesi (TR)
- American College of Dubai (AE)
- Pamukkale University (TR)
- Kocaeli Üniversitesi (TR)
- Shahid Beheshti University of Medical Sciences (IR)
- Gaziantep University (TR)
- Istanbul University (TR)
- Marmara University (TR)
- Gazi University (TR)
Publication Details
- Journal
- Research and Practice in Thrombosis and Haemostasis
- Published
- 2024-10-18
- DOI
- https://doi.org/10.1016/j.rpth.2024.102595
- Primary Topic
- Hemophilia Treatment and Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- European Commission
- Ministero della Salute
- Agenzia Italiana del Farmaco, Ministero della Salute