Phase 2 trial of avelumab in combination with gemcitabine in advanced leiomyosarcoma as a second‐line treatment (EAGLES, Korean Cancer Study Group UN18‐06)
The combination of avelumab and gemcitabine demonstrated promising efficacy and manageable safety in patients with advanced LMS who progressed on first-line therapy. Tumor-infiltrating lymphocyte density may be an important factor in predicting the response to combining immunotherapy with chemotherapy.
Authors
- Taebum Lee (ORCID: https://orcid.org/0000-0002-9472-0644)
- Wonyoung Choi (ORCID: https://orcid.org/0000-0002-8292-3903)
- Jung Yong Hong (ORCID: https://orcid.org/0000-0003-1363-9332)
- Koung Jin Suh (ORCID: https://orcid.org/0000-0002-1881-8738)
- Yoon Ji Choi (ORCID: https://orcid.org/0000-0002-1831-0555)
- Gyeong‐Won Lee (ORCID: https://orcid.org/0000-0002-1781-2262)
- Mi Sun Ahn (ORCID: https://orcid.org/0000-0002-7081-9826)
- Young Saing Kim (ORCID: https://orcid.org/0000-0003-0207-2617)
- Yu Jung Kim (ORCID: https://orcid.org/0000-0002-5037-0523)
- Chiyoon Oum
- Se Hyun Kim (ORCID: https://orcid.org/0000-0002-2292-906X)
- Sung Yong Oh (ORCID: https://orcid.org/0000-0002-8321-4113)
- Jeongkyu Kim (ORCID: https://orcid.org/0000-0002-8550-6654)
- Jeong Eun Kim (ORCID: https://orcid.org/0000-0001-9766-1531)
- Su Jin Lee (ORCID: https://orcid.org/0000-0003-3405-9935)
- Jin‐Hee Ahn (ORCID: https://orcid.org/0000-0003-3996-7596)
- Jeeyun Lee (ORCID: https://orcid.org/0000-0001-9536-8059)
- Jung Hoon Kim (ORCID: https://orcid.org/0000-0002-1106-8030)
- Miso Kim
- Juhyeon Jeong
Institutions
- Ulsan College (KR)
- Gachon University (KR)
- Ewha Womans University (KR)
- Korea University Medical Center (KR)
- Dong-A University Hospital (KR)
- Asan Medical Center (KR)
- Samsung Medical Center (KR)
- Seoul National University Hospital (KR)
- Seoul National University Bundang Hospital (KR)
- University of Ulsan (KR)
- Gachon University Gil Medical Center (KR)
- Gyeongsang National University Hospital (KR)
- National Institute of Fisheries Science (KR)
- National Cancer Center (KR)
- Pusan National University Yangsan Hospital (KR)
- Ajou University (KR)
- Sungkyunkwan University (KR)
Publication Details
- Journal
- Cancer
- Published
- 2024-10-18
- DOI
- https://doi.org/10.1002/cncr.35609
- Citations
- 4
- Primary Topic
- Sarcoma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.68
Funders
- Merck KGaA