Clinical Factors Associated With Suspicious <sup>18</sup> F-DCFPyL PSMA PET Activity in Patients Initially Managed With Radical Prostatectomy Including Prostate-Specific Antigen < 0.5 ng/mL
Over one-third of patients with PSAs < 0.2 ng/mL had imaging findings concerning for recurrence. Prior postoperative radiation was associated with higher rates of PSMA positivity among patients with PSA < 0.5 ng/mL, and half of patients with evidence of PSMA-avid distant metastatic disease underwent metastasis-directed therapy. PET-PSMA imaging at low PSAs can be considered to inform salvage therapies.
Authors
- Edward M. Schaeffer (ORCID: https://orcid.org/0000-0003-0699-1899)
- Eric V. Li (ORCID: https://orcid.org/0000-0002-5506-5755)
- Ashley E. Ross (ORCID: https://orcid.org/0000-0001-7044-9688)
- R. C. Bennett (ORCID: https://orcid.org/0009-0008-1335-7291)
- Austin Ho (ORCID: https://orcid.org/0000-0001-6016-9236)
- Ashorne K. Mahenthiran (ORCID: https://orcid.org/0000-0003-3409-2460)
- Hiten D. Patel (ORCID: https://orcid.org/0000-0003-4028-010X)
- Steven P. Rowe (ORCID: https://orcid.org/0000-0003-2897-4694)
- Hatice Savas (ORCID: https://orcid.org/0000-0002-9835-9630)
- Zequn Sun (ORCID: https://orcid.org/0000-0003-4177-9199)
- Clarissa Wong
- Sai Kaushik Shankar Ramesh Kumar
Institutions
- Northwestern University (US)
- University of North Carolina at Chapel Hill (US)
- Indiana University School of Medicine
- Indiana University – Purdue University Indianapolis (US)
Publication Details
- Journal
- The Journal of Urology
- Published
- 2024-10-18
- DOI
- https://doi.org/10.1097/ju.0000000000004298
- Citations
- 3
- Primary Topic
- Prostate Cancer Treatment and Research
- Type
- article
- Field-Weighted Citation Impact
- 1.26