Comparison of Oliceridine to Remifentanil for Optimal Analgesia in Mechanical Ventilation (CO-ROAM): Study Protocol for a Multicenter Randomized Controlled Trial
The primary outcome will be the percentage of time within target analgesia during study drug administration. Secondary outcomes will include gastrointestinal dysfunction, respiratory depression, sedative usage, mechanical ventilation duration, ICU stay length, extubation failure rate, etc. TRIAL REGISTRATION: NCT06454292. Registered on June 11, 2024.
Authors
- Xiaobo Huang (ORCID: https://orcid.org/0000-0002-6391-1333)
- Jing‐chao Luo (ORCID: https://orcid.org/0000-0001-9349-7543)
- Chun Pan (ORCID: https://orcid.org/0000-0002-6077-5882)
- Jun Shen (ORCID: https://orcid.org/0000-0001-9574-2418)
- Hongli He
- Sen Lu (ORCID: https://orcid.org/0000-0002-6565-7869)
- Xiaorui Fu (ORCID: https://orcid.org/0000-0003-4778-2284)
Institutions
- University of Electronic Science and Technology of China (CN)
- Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital (CN)
Publication Details
- Journal
- Pain and Therapy
- Published
- 2024-10-18
- DOI
- https://doi.org/10.1007/s40122-024-00669-4
- Citations
- 5
- Primary Topic
- Intensive Care Unit Cognitive Disorders
- Type
- article
- Field-Weighted Citation Impact
- 2.11