Plasma genome-wide mendelian randomization identifies potentially causal genes in idiopathic pulmonary fibrosis
This study demonstrated that genetically determined plasma levels of the BTRC, RIPK4, and LINC01252 genes, as well as methylation levels of cg00045227 (OR8U8), cg00577578 (GBAP1), cg07163735 (MAPT), cg14222479 (ARPM1), and cg19263494 (PMF1), have causal influences on the risk of IPF.
Authors
- Jiejun Zhou
- Anqi Li (ORCID: https://orcid.org/0000-0002-3037-9483)
- Mingwei Chen (ORCID: https://orcid.org/0000-0002-1236-6881)
- Puyu Shi (ORCID: https://orcid.org/0000-0002-3477-0148)
- Kun Zhang (ORCID: https://orcid.org/0000-0002-1088-5813)
Institutions
- First Affiliated Hospital of Xi'an Jiaotong University (CN)
Publication Details
- Journal
- Respiratory Research
- Published
- 2024-10-18
- DOI
- https://doi.org/10.1186/s12931-024-03008-5
- Citations
- 4
- Primary Topic
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Type
- article
- Field-Weighted Citation Impact
- 1.68