Detection of Human Y Chromosome and the SRY Gene in Fecal Samples of Female Patients Following Fecal Microbiota Transplantation
These observations clearly demonstrate the presence of ChrY and SRY gene signal in stool samples collected from male patients. The presence of increased ChrY in the stool samples of female RCDI patients after FMT from a male donor suggests possible engraftment of exfoliated intestinal epithelial cells in a subset of these patients.
Authors
- Sudhir Dutta (ORCID: https://orcid.org/0000-0003-3478-9225)
- Padmanabhan P. Nair (ORCID: https://orcid.org/0000-0002-8925-1193)
- Sandeep Verma (ORCID: https://orcid.org/0000-0001-8072-6693)
- Elad Firnberg (ORCID: https://orcid.org/0000-0003-1835-853X)
- Laila Phillips (ORCID: https://orcid.org/0000-0002-9565-0246)
Institutions
- University of Maryland, Baltimore (US)
- Johns Hopkins University (US)
- Johns Hopkins Medicine (US)
- Sinai Hospital (US)
Publication Details
- Journal
- Gastro Hep Advances
- Published
- 2024-10-18
- DOI
- https://doi.org/10.1016/j.gastha.2024.10.008
- Primary Topic
- Parasitic Infections and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 0.00