Biological aging accelerates hepatic fibrosis: Insights from the NHANES 2017–2020 and genome-wide association study analysis
This study emphasized the link between biological aging and fibrosis in young to middle-aged obese MASLD patients. We introduced phenotypic age as a clinical indicator and identified APOLD1 as a potential therapeutic target.
Authors
- Jiawei Ding (ORCID: https://orcid.org/0009-0003-0684-6648)
- Rui Wu (ORCID: https://orcid.org/0000-0002-4956-470X)
- J. Zhao (ORCID: https://orcid.org/0009-0005-6703-4779)
- Zheyu Fang (ORCID: https://orcid.org/0000-0001-5780-0728)
- Huiying Zhou (ORCID: https://orcid.org/0000-0003-2808-4114)
- Chen Ruan (ORCID: https://orcid.org/0000-0003-0158-1970)
- Tao Zhang (ORCID: https://orcid.org/0000-0003-4861-0679)
- Cheng Wang (ORCID: https://orcid.org/0000-0001-5087-3027)
- Lei Zhang (ORCID: https://orcid.org/0000-0001-7769-7377)
- Zhenhua Hu
- Jie Zhou (ORCID: https://orcid.org/0000-0001-6521-1384)
- Huilin Zheng (ORCID: https://orcid.org/0000-0003-3845-6612)
Institutions
- Wenzhou Medical University (CN)
- First Affiliated Hospital of Wenzhou Medical University (CN)
- Tongde Hospital of Zhejiang Province (CN)
- First Affiliated Hospital Zhejiang University (CN)
- Zhejiang University of Technology (CN)
- Zhejiang University (CN)
Publication Details
- Journal
- Annals of Hepatology
- Published
- 2024-10-18
- DOI
- https://doi.org/10.1016/j.aohep.2024.101579
- Citations
- 7
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 2.71
Funders
- National Key Research and Development Program of China
- Science and Technology Program of Zhejiang Province