Functional Connectivity Relationships to Longitudinal Motor Outcomes Differ in Very Preterm Children With and Without Brain Injury

In VPT children with brain injury, interhemispheric motor cortex FC was related to motor deficits at 5-year assessment, similar to previous findings at 2 years. In uninjured children, FC-measured disruption of the motor system during the neonatal period was associated with motor planning/coordination difficulties that were not apparent on 2-year assessment but emerged at 5 years, suggesting that the neural basis of these deficits was established very early in life. Subsequently, 2-year follow-up may not be sufficient to detect milder motor deficits in VPT children, and they should be monitored for motor difficulties throughout the preschool years. For all VPT children, FC at term-equivalent age has the potential to improve our ability to predict disability before it presents behaviorally.

Authors

Institutions

Publication Details

Journal
Neurology Clinical Practice
Published
2024-10-18
DOI
https://doi.org/10.1212/cpj.0000000000200397
Citations
2
Primary Topic
Infant Development and Preterm Care
Type
article
Field-Weighted Citation Impact
2.22
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Functional Connectivity Relationships to Longitudinal Motor Outcomes Differ in Very Preterm Children With and Without Brain Injury

Cynthia Rogers, Dominique Meyer, Rachel E. Lean, Thomas L. Rodebaugh et al.
2 citations
Neurology Clinical Practice
Infant Development and Preterm Care
2.22
article

Functional Connectivity Relationships to Longitudinal Motor Outcomes Differ in Very Preterm Children With and Without Brain Injury

Cynthia Rogers, Dominique Meyer, Rachel E. Lean, Thomas L. Rodebaugh, Peppar E.P. Cyr, Rebecca G. Brady, Christopher D. Smyser, Joshua S. Shimony, Jeanette K. Kenley, Jeffrey J. Neil, Sydney Janet Kaplan, Dimitrios Alexopoulos
article en
2 citations

Abstract

In VPT children with brain injury, interhemispheric motor cortex FC was related to motor deficits at 5-year assessment, similar to previous findings at 2 years. In uninjured children, FC-measured disruption of the motor system during the neonatal period was associated with motor planning/coordination difficulties that were not apparent on 2-year assessment but emerged at 5 years, suggesting that the neural basis of these deficits was established very early in life. Subsequently, 2-year follow-up may not be sufficient to detect milder motor deficits in VPT children, and they should be monitored for motor difficulties throughout the preschool years. For all VPT children, FC at term-equivalent age has the potential to improve our ability to predict disability before it presents behaviorally.

Neurology Clinical PracticeVol. 15(1)
Mallinckrodt (United States) (US)
Openalex Percentile: Top 11%
Infant Development and Preterm Care
2.22
DOIOpen Access PDFOpenAlex
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.