EFEITO ANTIFÚNGICO DE FITOTERÁPICOS FRENTE A CANDIDA ALBICANS E CANDIDA GLABRATA: REVISÃO INTEGRATIVA

Invasive fungal infections (IFIs) develop as a result of factors that are primarily the vulnerability of the compromised immune system. Among the main fungi that cause IFIs lies Candida sp., which has non-pathogenic control in the body, except when there is an imbalance in the human microbiota. Therefore, in the quest to contain oral fungal origins, bioactives have been used as antifungals, as essential oils can be obtained from plants that have aromatic substances with antifungal action. Being, phytotherapy a low cost alternative and natural effect in the treatment of these diseases. The objective was to analyze the antifungal properties and toxicity of ginger (Zingiber officinale Roscoe) on strains of Candida Albicans ATCC® 18804™; Candida glabrata ATCC® 728™. This is an integrative review study that used the following descriptors: “Fungicidal activity of ginger”, “Candida albicans”, “Candida glabrata”, “Oral mucosa” and “Oral candidiasis”. Through the analysis of the results of the articles, we showed that the development of resistant strains has the ability to form biofilms, which makes the treatment even more difficult, but the use of ginger extract, in a specific amount, is capable of eliminating C. albicans and C. glabrata from root canals.