Gestational diabetes exacerbates intrauterine microbial exposure induced intestinal microbiota change in offspring contributing to increased immune response
Our investigation has revealed a noteworthy correlation between gestational diabetes and intrauterine microbial exposure, as well as alterations in the neonatal microbiota and activation of immune responses. These findings highlight the gestational diabetes's role on offspring's gut microbiota and immune system interactions with early-life pathogen exposure.
Authors
- Ping Yang (ORCID: https://orcid.org/0000-0001-7960-6248)
- Irakoze Laurent (ORCID: https://orcid.org/0000-0003-0287-8901)
- Xiaoqiu Xiao (ORCID: https://orcid.org/0000-0002-4568-8772)
- Xinyu Li (ORCID: https://orcid.org/0000-0001-7203-7417)
- Juncheng Liu (ORCID: https://orcid.org/0000-0003-1754-391X)
- Yan Chen (ORCID: https://orcid.org/0000-0002-9425-1526)
Institutions
- Chongqing University (CN)
- The Affiliated Yongchuan Hospital of Chongqing Medical University (CN)
- Chongqing Emergency Medical Center (CN)
- Chongqing Cancer Hospital (CN)
- First People's Hospital of Chongqing (CN)
- Chongqing Medical University (CN)
Publication Details
- Journal
- Nutrition and Diabetes
- Published
- 2024-10-18
- DOI
- https://doi.org/10.1038/s41387-024-00346-7
- Citations
- 8
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 1.87
Funders
- National Natural Science Foundation of China