Brain-targeted ursolic acid nanoparticles for anti-ferroptosis therapy in subarachnoid hemorrhage
Brain-targeted HA-PEG-UA NPs was successfully developed and hold the potential to enhance SAH prognosis by limiting neuronal ferroptosis via modulation of the Nrf-2/SLC7A11/GPX4 signal.
Authors
- Xinyi Zhu (ORCID: https://orcid.org/0000-0002-7361-8958)
- Gang Deng (ORCID: https://orcid.org/0000-0002-0136-2535)
- Yong Li (ORCID: https://orcid.org/0000-0002-8910-9787)
- Mingchang Li (ORCID: https://orcid.org/0000-0003-4019-8886)
- Yangzhi Qi (ORCID: https://orcid.org/0000-0002-7515-3410)
- Qingsong Ye (ORCID: https://orcid.org/0000-0002-2868-9247)
- Xiaobing Jiang
- Yujia Guo
- Youdong Zhou
- Qingyu Zhao (ORCID: https://orcid.org/0000-0002-6304-9528)
- Baohui Liu (ORCID: https://orcid.org/0000-0001-5821-6945)
- Wei Xiong (ORCID: https://orcid.org/0000-0002-7769-7569)
- Qianxue Chen (ORCID: https://orcid.org/0000-0002-9413-1030)
Institutions
- Union Hospital (HK)
- Wuhan University (CN)
- Renmin Hospital of Wuhan University (CN)
- Huazhong University of Science and Technology (CN)
Publication Details
- Journal
- Journal of Nanobiotechnology
- Published
- 2024-10-18
- DOI
- https://doi.org/10.1186/s12951-024-02866-x
- Citations
- 13
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 5.45