Expression of Myeloperoxidase in Patient-Derived Endothelial Colony-Forming Cells—Associations with Coronary Artery Disease and Mitochondrial Function
MPO is present in the nucleus of ECFCs. In non-CAD ECFCs, MPO expression is linked to upregulated mitochondrial-antioxidant genes, whereas in CAD ECFCs, it is associated with greater mitochondrial dysfunction.
Authors
- Giannie Barsha (ORCID: https://orcid.org/0000-0002-2898-6794)
- Gemma Alexandra Figtree (ORCID: https://orcid.org/0000-0002-5080-6083)
- Michael P. Gray (ORCID: https://orcid.org/0000-0003-1154-3011)
- Charles Mifsud
- Stephen T. Vernon
- Elijah Genetzakis (ORCID: https://orcid.org/0009-0009-4381-7268)
- Stuart M. Grieve (ORCID: https://orcid.org/0000-0002-2712-157X)
- Weiqian Eugene Lee (ORCID: https://orcid.org/0000-0002-2232-1759)
- Joshua Vescovi (ORCID: https://orcid.org/0009-0007-0845-6204)
- Trinh Xuan Nguyen (ORCID: https://orcid.org/0000-0003-1294-7739)
Institutions
- Australian Regenerative Medicine Institute (AU)
- Monash University (AU)
Publication Details
- Journal
- Biomolecules
- Published
- 2024-10-16
- DOI
- https://doi.org/10.3390/biom14101308
- Citations
- 5
- Primary Topic
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 1.20
Funders
- Heart Research Australia
- Office of Health and Medical Research
- Medical Research Council
- National Health and Medical Research Council