Epidemiological and Clinical Features of a Large Blastomycosis Outbreak at a Paper Mill in Michigan
This was the largest documented blastomycosis outbreak in the United States. Epidemiologic evidence indicated exposures occurred at or near the mill, and genomic findings suggested a common exposure source. Patients with diabetes may have increased risk of hospitalization, and elevated urine antigen titers could indicate greater disease severity. Early suspicion of blastomycosis may prompt earlier diagnosis and treatment, potentially reducing unnecessary antibiotic prescriptions and improving patient outcomes.
Authors
- Angie M. Schooley
- Lalitha Gade (ORCID: https://orcid.org/0000-0002-9264-9952)
- Ian Hennessee (ORCID: https://orcid.org/0000-0001-8807-9566)
- Dallas Shi
- Jean M. Cox‐Ganser (ORCID: https://orcid.org/0000-0001-8140-264X)
- Kimberly McCullor
- Jim Collins
- Bernhard Hirt (ORCID: https://orcid.org/0000-0002-6018-7191)
- Heather M. Blankenship (ORCID: https://orcid.org/0000-0003-2678-562X)
- Mitsuru Toda (ORCID: https://orcid.org/0000-0002-5904-6658)
- Adam L. Hughes (ORCID: https://orcid.org/0000-0002-7095-3793)
- David N. Weissman (ORCID: https://orcid.org/0000-0003-2421-7231)
- Mary Grace Stobierski
- Ryan F. LeBouf (ORCID: https://orcid.org/0000-0002-9894-9251)
- Dallas J. Smith (ORCID: https://orcid.org/0000-0001-5707-528X)
- Marie A. de Perio (ORCID: https://orcid.org/0000-0001-5100-8422)
- Jevon McFadden (ORCID: https://orcid.org/0009-0004-1038-5765)
- Shawn R. Lockhart (ORCID: https://orcid.org/0000-0002-4383-5994)
- M. Nawaz (ORCID: https://orcid.org/0000-0002-6029-6136)
- Perri C. Callaway (ORCID: https://orcid.org/0000-0002-5135-0698)
- Arianna Miles-Jay (ORCID: https://orcid.org/0000-0001-5332-0946)
- Jeremy A.W. Gold (ORCID: https://orcid.org/0000-0002-5054-7616)
- Melissa Millerick-May (ORCID: https://orcid.org/0000-0003-0924-9278)
- Samantha Williams (ORCID: https://orcid.org/0000-0002-8751-9571)
- Tom Chiller (ORCID: https://orcid.org/0000-0002-2251-8033)
- Rachel L. Bailey (ORCID: https://orcid.org/0000-0001-6496-8692)
- T. Heyer
- Lindsay A. Parnell (ORCID: https://orcid.org/0000-0001-5598-6485)
- Ju‐Hyeong Park (ORCID: https://orcid.org/0000-0003-4419-9341)
- Stella E. Hines (ORCID: https://orcid.org/0000-0002-8350-9448)
- Michael Snyder
- Anastasia P. Litvintseva (ORCID: https://orcid.org/0000-0003-1086-8041)
- Allyson W. O’Connor
- Rebecca E. Kramer
- Marty Soehnlen
- Sara Palmer
- Marcia Stanton
- Robert K. Yin
- Rebecca Reik
- R. M. Stewart
Institutions
- Centers for Disease Control and Prevention (US)
- Michigan Department of Health and Human Services (US)
- National Institute for Occupational Safety and Health (US)
- Office of the Director (US)
- The Centers (US)
- Epidemic Intelligence Service (US)
Publication Details
- Journal
- Clinical Infectious Diseases
- Published
- 2024-10-18
- DOI
- https://doi.org/10.1093/cid/ciae513
- Citations
- 10
- Primary Topic
- Fungal Infections and Studies
- Type
- article
- Field-Weighted Citation Impact
- 3.87
Funders
- U.S. Department of Health and Human Services
- Michigan Department of Health and Human Services
- Centers for Disease Control and Prevention