Rhetoric Questions for Surgeons in the Transcatheter Edge- to- Edge Repair and Artificial Intelligence Era

The advancement in minimally invasive approach via a transcatheter route for dealing with valvular regurgitation has been exponential the last decade. State of the art devices and complex algorithms produced utilising artificial intelligence technologies dominating our life and will be the near future direction of modern healthcare systems. The evolving technique of edge- to- edge repair for the management of secondary Mitral Regurgitation (MR) has revealed contradictory results in the past as it has been depicted in two major clinical trials which sparked major debates [1,2]. The 5- year data of the COAPT trial [3] published last year shows survival benefit for the patients but despite this profound benefit, the mortality and the hospitalisation rate remains high in this cohort of patients. The advancement in artificial intelligence technology and the progress of regenerative medicine may constitute the mean on the effort of developing new therapeutical techniques for the complex secondary mitral regurgitation.