Partial Protection of Goats against Haemonchus contortus Achieved with ADP-Ribosylation Factor 1 Encapsulated in PLGA Nanoparticles
These findings indicate that the nanovaccine expressing rHcARF1 offers significant protective efficacy against <i>H. contortus</i> infection in goats. The results also suggest the need for more precise optimization of the antigen dose or a reassessment of the vaccination regimen. Additionally, the small sample size limits the statistical rigor and the broader applicability of the findings.
Authors
- Muhammad Waqqas Hasan (ORCID: https://orcid.org/0000-0001-8560-7714)
- Shakeel Ahmed Lakho (ORCID: https://orcid.org/0000-0003-4777-5973)
- Javaid Ali Gadahi (ORCID: https://orcid.org/0000-0001-6006-1954)
- Muhammad Haseeb (ORCID: https://orcid.org/0000-0002-2587-0171)
- Mingmin Lu (ORCID: https://orcid.org/0000-0002-7343-7815)
- Muhammad Tahir Aleem (ORCID: https://orcid.org/0000-0001-8899-2777)
- Muhammad Ehsan (ORCID: https://orcid.org/0000-0001-5314-5869)
- Xiaokai Song (ORCID: https://orcid.org/0000-0003-0102-0938)
- Qiangqiang Wang (ORCID: https://orcid.org/0000-0002-5506-6539)
- Xiangrui Li (ORCID: https://orcid.org/0000-0002-7143-6827)
- Ali Haider (ORCID: https://orcid.org/0000-0001-8755-2454)
- Lixin Xu (ORCID: https://orcid.org/0000-0003-1458-3676)
- Ruofeng Yan
Institutions
- Nanjing Agricultural University (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- Vaccines
- Published
- 2024-10-18
- DOI
- https://doi.org/10.3390/vaccines12101188
- Citations
- 2
- Primary Topic
- Helminth infection and control
- Type
- article
- Field-Weighted Citation Impact
- 1.28