Optimal risk thresholds for prescribing statins as primary prevention of cardiovascular disease in Iranian general population: a benefit-harm modelling study
The desirable 10-year risk thresholds for statin prescription in the primary prevention of CVD vary by age and gender, ranging from 18 to 28%, encompassing a spectrum of outcomes from angina to CVD mortality. These results suggest hard-CVD risk thresholds of 7.5% to 10% for both sexes.
Authors
- Hassan Saadati
- Farzad Hadaegh (ORCID: https://orcid.org/0000-0002-8935-2744)
- Goodarz Danaei (ORCID: https://orcid.org/0000-0003-2456-5463)
- Hamid Reza Baradaran (ORCID: https://orcid.org/0000-0002-5070-5864)
- Ewout W. Steyerberg (ORCID: https://orcid.org/0000-0002-7787-0122)
- Davood Khalili (ORCID: https://orcid.org/0000-0003-4956-1039)
- Mark Woodward
Institutions
- Iran University of Medical Sciences (IR)
- The George Institute for Global Health (GB)
- University of Aberdeen (GB)
- Leiden University Medical Center (NL)
- Erasmus MC (NL)
- UNSW Sydney (AU)
- Research Institute for Endocrine Sciences (IR)
- The George Institute for Global Health (AU)
- Harvard Global Health Institute (US)
- North Khorasan University of Medical Sciences (IR)
- Imperial College London (GB)
- Shahid Beheshti University of Medical Sciences (IR)
- Erasmus University Rotterdam (NL)
Publication Details
- Journal
- BMC Cardiovascular Disorders
- Published
- 2024-10-18
- DOI
- https://doi.org/10.1186/s12872-024-04242-x
- Citations
- 1
- Primary Topic
- Lipoproteins and Cardiovascular Health
- Type
- article
- Field-Weighted Citation Impact
- 0.57
Funders
- Harvard T.H. Chan School of Public Health
- National Institute for Medical Research Development
- Department of Global Health and Population, Harvard T.H. Chan School of Public Health