MIR194-2HG, a miRNA host gene activated by HNF4A, inhibits gastric cancer by regulating microRNA biogenesis
The dysregulated MIR194-2HG/BTF3L4 axis is responsible for GC progression. Targeting HNF4A to inhibit miR-192/194 expression may be a promising strategy for overcoming GC.
Authors
- Shanshan Qin (ORCID: https://orcid.org/0009-0003-1722-0392)
- Dandan Li (ORCID: https://orcid.org/0000-0002-6224-8867)
- Qiwei Guo (ORCID: https://orcid.org/0000-0001-5558-1971)
- Zidi Wang (ORCID: https://orcid.org/0009-0007-3499-4719)
- Hongcui Cao
Institutions
- Hubei University of Medicine (CN)
Publication Details
- Journal
- Biology Direct
- Published
- 2024-10-18
- DOI
- https://doi.org/10.1186/s13062-024-00549-z
- Citations
- 11
- Primary Topic
- MicroRNA in disease regulation
- Type
- article
- Field-Weighted Citation Impact
- 3.14
Funders
- National Natural Science Foundation of China