Alterations of the gut microbiome in HIV infection highlight human anelloviruses as potential predictors of immune recovery
Advanced HIV-1 infection was associated with marked alterations in the virome composition, in particular a remarkable expansion of human anelloviruses, with a gradual restoration after ART initiation. In addition to CD4 T cell counts, anellovirus sequence detection might be useful to predict and monitor immune recovery. This study confirms data on the bacteriome and expands our knowledge on the viral component of the gut microbiome in HIV-1 infection. Video Abstract.
Authors
- Sandra Pinto-Cardoso (ORCID: https://orcid.org/0000-0001-8957-4972)
- Daniela Garrido-Rodríguez (ORCID: https://orcid.org/0000-0001-7289-1429)
- Amy Peralta-Prado (ORCID: https://orcid.org/0000-0002-6379-9134)
- Karla Romero-Mora
- Alma Rincón-Rubio (ORCID: https://orcid.org/0000-0002-0313-2792)
- Monserrat Chávez-Torres
- Santiago Ávila‐Ríos (ORCID: https://orcid.org/0000-0003-3371-4248)
- Célia Boukadida (ORCID: https://orcid.org/0000-0002-1744-0083)
- Gustavo Reyes-Terán (ORCID: https://orcid.org/0000-0002-4115-4888)
Institutions
- Hospitales Regionales de Alta Especialidad (MX)
- Instituto Nacional de Enfermedades Respiratorias (MX)
Publication Details
- Journal
- Microbiome
- Published
- 2024-10-17
- DOI
- https://doi.org/10.1186/s40168-024-01925-7
- Citations
- 10
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 2.34
Funders
- Institute of Nuclear Energy Research