Serum and mucosal antibody-mediated protection and identification of asymptomatic respiratory syncytial virus infection in community-dwelling older adults in Europe
This study provides insights into antibody-mediated protection for symptomatic RSV infection in a community-dwelling older-adult population and establishes a threshold to identify asymptomatic RSV infection using a data-driven approach.
Authors
- Arangassery Rosemary Bastian
- Samuel Coenen (ORCID: https://orcid.org/0000-0002-1238-8052)
- Simon B. Drysdale (ORCID: https://orcid.org/0000-0002-6350-6557)
- Peter Openshaw (ORCID: https://orcid.org/0000-0002-7220-2555)
- Marjolein Crabbe
- Sunita S. Balla-Jhagjhoorsingh
- Deniz Öner (ORCID: https://orcid.org/0000-0002-2326-6667)
- Louis Bont
- Koos Korsten (ORCID: https://orcid.org/0000-0003-2451-4113)
- Theo Verheij (ORCID: https://orcid.org/0000-0002-0166-1498)
- Charlotte Vernhes (ORCID: https://orcid.org/0009-0007-9915-3232)
- Jonathan De Smedt (ORCID: https://orcid.org/0000-0002-8374-4923)
- Jeroen Aerssens (ORCID: https://orcid.org/0000-0002-9254-4800)
- Bruno Salaun (ORCID: https://orcid.org/0000-0002-8927-8660)
- Joanne Wildenbeest (ORCID: https://orcid.org/0000-0003-3661-551X)
- Andrew J. Pollard (ORCID: https://orcid.org/0000-0001-7361-719X)
- Christopher Butler (ORCID: https://orcid.org/0000-0002-0102-3453)
- Annick Moureau (ORCID: https://orcid.org/0000-0002-5306-2833)
- Niels Adriaenssens (ORCID: https://orcid.org/0000-0002-7957-1177)
- Kim Thys (ORCID: https://orcid.org/0000-0002-0400-6915)
- Salo N. Ooft
Institutions
- Janssen (Belgium) (BE)
- University of Antwerp (BE)
- St George's, University of London (GB)
- Sanofi (France) (FR)
- University Medical Center Utrecht (NL)
- National Institute for Health and Care Research (GB)
- University of Oxford (GB)
- GlaxoSmithKline (Belgium) (BE)
- Janssen (Netherlands) (NL)
- Wilhelmina Children's Hospital (NL)
- Imperial College London (GB)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2024-10-18
- DOI
- https://doi.org/10.3389/fimmu.2024.1448578
- Citations
- 3
- Primary Topic
- Respiratory viral infections research
- Type
- article
- Field-Weighted Citation Impact
- 1.16
Funders
- Pfizer
- AstraZeneca
- GlaxoSmithKline
- Sanofi
- Moderna
- National Institute for Health and Care Research
- Department of Health and Social Care
- European Commission
- Innovative Medicines Initiative
- Agency for Healthcare Research and Quality
- Sanofi Pasteur
- Janssen Pharmaceuticals