Pharmacological blockade of the mast cell MRGPRX2 receptor supports investigation of its relevance in skin disorders
These data fully support the investigation of MRGPRX2 receptor antagonists in mast cell-driven allergic skin disorders such as chronic spontaneous urticaria.
Authors
- Theresa J. Roethke
- Colin H. Macphee
- Daniel V. Paone
- Stuart Pearson
- Per Stahl Skov (ORCID: https://orcid.org/0000-0002-2481-4549)
- Xinzhong Dong (ORCID: https://orcid.org/0000-0002-9750-7718)
- K Baumann (ORCID: https://orcid.org/0000-0002-0656-3897)
- Deborah A. Goldspink (ORCID: https://orcid.org/0000-0003-2287-4844)
- Peng Qi (ORCID: https://orcid.org/0000-0003-1732-7176)
- Zining Wu
Institutions
- Howard Hughes Medical Institute (US)
- Johns Hopkins University (US)
- Johns Hopkins Medicine (US)
- Age UK (GB)
- GlaxoSmithKline (United States) (US)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2024-10-18
- DOI
- https://doi.org/10.3389/fimmu.2024.1433982
- Citations
- 15
- Primary Topic
- Mast cells and histamine
- Type
- article
- Field-Weighted Citation Impact
- 3.61