Benefit of dual bronchodilator therapy on exacerbations in former and current smokers with chronic obstructive pulmonary disease in real-world clinical practice: a multicenter validation study (TOReTO)
The three fixed-dose combinations of LABA/LAMA showed no difference in reducing exacerbations in former smokers but did show differences in current smokers. This trend has clinical significance, and future research will be conducted to control influencing variables to validate this point. However, due to the non-randomized study design, these findings should be interpreted with caution.
Authors
- Ning‐Hung Chen (ORCID: https://orcid.org/0000-0002-8387-9318)
- Meng‐Jer Hsieh (ORCID: https://orcid.org/0000-0002-2077-0470)
- Chi‐Wei Tao (ORCID: https://orcid.org/0000-0001-5170-1382)
- Yao‐Kuang Wu (ORCID: https://orcid.org/0000-0001-7898-6963)
- Yu‐Feng Wei (ORCID: https://orcid.org/0000-0002-6380-3527)
- Shih‐Feng Liu (ORCID: https://orcid.org/0000-0003-1394-5401)
- Tsung‐Ming Yang (ORCID: https://orcid.org/0000-0002-9241-2816)
- Ping‐Hung Kuo (ORCID: https://orcid.org/0000-0003-3756-3395)
- Ching‐Lung Liu (ORCID: https://orcid.org/0000-0002-7811-8864)
- Shih-Lung Cheng (ORCID: https://orcid.org/0000-0003-0111-3157)
- Ming-Cheng Chan
- Yu-Ting Lai (ORCID: https://orcid.org/0000-0001-5289-5051)
- Ming‐Shian Lin
- Ying‐Huang Tsai
- Wu‐Huei Hsu
Institutions
- National Chung Hsing University (TW)
- Chang Gung University (TW)
- China Medical University (TW)
- Mackay Memorial Hospital (TW)
- Chang Gung Memorial Hospital (TW)
- E-Da Hospital (TW)
- Taichung Veterans General Hospital (TW)
- Kaohsiung Chang Gung Memorial Hospital (TW)
- Taipei Tzu Chi Hospital (TW)
- Cheng Hsin General Hospital (TW)
- Far Eastern Memorial Hospital (TW)
- Chia-Yi Christian Hospital (TW)
- Linkou Chang Gung Memorial Hospital (TW)
- China Medical University Hospital (TW)
- National Taiwan University Hospital (TW)
- Xiamen Chang Gung Hospital (CN)
- Chiayi Chang Gung Memorial Hospital (TW)
- I-Shou University (TW)
- Yuan Ze University (TW)
Publication Details
- Journal
- Respiratory Research
- Published
- 2024-10-17
- DOI
- https://doi.org/10.1186/s12931-024-02971-3
- Citations
- 1
- Primary Topic
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Type
- article
- Field-Weighted Citation Impact
- 0.42