Quantifying patients’ preferences on tradeoffs between mortality risk and reduced need for target vessel revascularization for claudication
Most patients in the study would accept some incremental increase in 5-year mortality risk to reduce the 2-year and 5-year risks of CDTVR by 20 and 10 percentage points, respectively. However, significant patient-level variability in risk tolerance underscores the need for systematic approaches to support benefit-risk decision making.
Authors
- W. Schuyler Jones (ORCID: https://orcid.org/0000-0002-7288-9596)
- Jui‐Chen Yang (ORCID: https://orcid.org/0000-0001-8229-6578)
- Jessica P. Simons (ORCID: https://orcid.org/0000-0002-6249-8292)
- Anindita Saha (ORCID: https://orcid.org/0000-0003-0306-4264)
- Andrew Farb
- Michelle E. Tarver (ORCID: https://orcid.org/0000-0001-8768-6532)
- Sahil A. Parikh (ORCID: https://orcid.org/0000-0002-0551-5885)
- Olufemi Babalola (ORCID: https://orcid.org/0000-0003-3326-7775)
- Allen L. Chen
- Eric A. Secemsky (ORCID: https://orcid.org/0000-0003-3861-3163)
- Matthew A. Corriere (ORCID: https://orcid.org/0000-0002-7415-0322)
- Juan Marcos González (ORCID: https://orcid.org/0000-0002-5386-0907)
- David Gebben
- Misti Malone
- Jessie Sutphin (ORCID: https://orcid.org/0000-0002-2000-3677)
- Eva Rorer
- F. Reed Johnson (ORCID: https://orcid.org/0000-0002-7572-2150)
- Shelby D. Reed (ORCID: https://orcid.org/0000-0002-7654-4464)
- Matthew J. Wallace
- Mitchell W. Krucoff
- Jennifer Tsapatsaris
Institutions
- Beth Israel Deaconess Medical Center (US)
- United States Food and Drug Administration (US)
- Johnson & Johnson (United States) (US)
- Center for Devices and Radiological Health (US)
- Duke University (US)
- University of Michigan (US)
- Columbia University Irving Medical Center (US)
- Clinical Research Institute (US)
- Memorial Medical Center (US)
- Duke University Health System (US)
- UMass Memorial Medical Center (US)
- The Ohio State University (US)
Publication Details
- Journal
- Vascular Medicine
- Published
- 2024-10-16
- DOI
- https://doi.org/10.1177/1358863x241290233
- Citations
- 2
- Primary Topic
- Peripheral Artery Disease Management
- Type
- article
- Field-Weighted Citation Impact
- 1.15
Funders
- U.S. Food and Drug Administration