Schizophrenia, Off-Label Antipsychotics, and Dementia Risk in People With HIV

This study demonstrates that among PLWH, history of schizophrenia or off-label antipsychotic medication use are associated with substantial increases in dementia incidence. Furthermore, propensity score-matched control analysis reveals that HIV infection itself is independently and significantly associated with elevated dementia risk.

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Publication Details

Journal
JAIDS Journal of Acquired Immune Deficiency Syndromes
Published
2024-10-17
DOI
https://doi.org/10.1097/qai.0000000000003545
Primary Topic
HIV-related health complications and treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Schizophrenia, Off-Label Antipsychotics, and Dementia Risk in People With HIV

Tammy H. Cummings, Michael Shtutman, S. Scott Sutton, Joseph Magagnoli et al.
JAIDS Journal of Acquired Immune Deficiency Syndromes
HIV-related health complications and treatments
article

Schizophrenia, Off-Label Antipsychotics, and Dementia Risk in People With HIV

Tammy H. Cummings, Michael Shtutman, S. Scott Sutton, Joseph Magagnoli, Michael D. Wyatt
article en

Abstract

This study demonstrates that among PLWH, history of schizophrenia or off-label antipsychotic medication use are associated with substantial increases in dementia incidence. Furthermore, propensity score-matched control analysis reveals that HIV infection itself is independently and significantly associated with elevated dementia risk.

JAIDS Journal of Acquired Immune Deficiency SyndromesVol. 98(2)
University of South Carolina (US), Columbia VA Health Care System (US), Dorn Research Institute (US)
Good health and well-being
Openalex Percentile: Top 69%
HIV-related health complications and treatments
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