Outcomes After Brexucabtagene Autoleucel Administered as a Standard Therapy for Adults With Relapsed/Refractory B-Cell ALL
Similar to ZUMA-3, high rates of MRD-negative CR were observed after brexu-cel treatment for R/R B-ALL. The use of HCT as consolidation after brexu-cel resulted in improved PFS.
Authors
- Jozal Moore (ORCID: https://orcid.org/0000-0003-4811-5790)
- Lori S. Muffly (ORCID: https://orcid.org/0000-0002-9887-6136)
- Melhem Solh (ORCID: https://orcid.org/0000-0003-3766-5623)
- Rawan Faramand (ORCID: https://orcid.org/0000-0001-7750-781X)
- Danielle Bradshaw (ORCID: https://orcid.org/0009-0001-7721-3747)
- Wendy Stock (ORCID: https://orcid.org/0000-0002-8349-9200)
- Joshua Sasine (ORCID: https://orcid.org/0000-0001-9866-462X)
- Catherine J. Lee (ORCID: https://orcid.org/0000-0003-2587-8955)
- Simone E. Dekker (ORCID: https://orcid.org/0000-0002-0634-3034)
- George Yaghmour (ORCID: https://orcid.org/0000-0002-6988-3556)
- Paul Shaughnessy (ORCID: https://orcid.org/0000-0003-4023-3864)
- Michal Kubiak (ORCID: https://orcid.org/0000-0002-1647-4038)
- Santiago Mercadal (ORCID: https://orcid.org/0000-0003-4741-7885)
- Navneet S. Majhail (ORCID: https://orcid.org/0000-0001-7082-891X)
- Divya Koura
- Marlise Rachael Luskin (ORCID: https://orcid.org/0000-0002-5781-4529)
- Matthew P. Connor (ORCID: https://orcid.org/0000-0003-1186-0623)
- Vinod A. Pullarkat (ORCID: https://orcid.org/0000-0001-9129-3424)
- Akash Mukherjee (ORCID: https://orcid.org/0000-0001-6762-8976)
- Bijal Shah (ORCID: https://orcid.org/0000-0003-4328-6021)
- Naveed Ahmed (ORCID: https://orcid.org/0000-0002-4780-9945)
- Marc S. Schwartz (ORCID: https://orcid.org/0009-0007-6060-2723)
- Luke Mountjoy (ORCID: https://orcid.org/0000-0001-5140-8346)
- Caspian Oliai (ORCID: https://orcid.org/0000-0002-6368-8557)
- Jessica Leonard (ORCID: https://orcid.org/0000-0001-5576-0048)
- Vishal Gupta
- Ibrahim Taha Aldoss (ORCID: https://orcid.org/0000-0001-9564-4498)
- Gregory W. Roloff (ORCID: https://orcid.org/0000-0003-2109-5152)
- Noam E. Kopmar (ORCID: https://orcid.org/0000-0001-8710-9217)
- Muthu Veeraputhiran
- Evan Chris Chen (ORCID: https://orcid.org/0000-0002-9218-215X)
- Rasmus T. Hoeg (ORCID: https://orcid.org/0000-0001-5476-3247)
- LaQuisa C. Hill (ORCID: https://orcid.org/0000-0003-4304-935X)
- Bhagirathbhai Dholaria (ORCID: https://orcid.org/0000-0003-2371-3655)
- Betsy Blunk
- Kristen M. O'Dwyer
- John Mathews (ORCID: https://orcid.org/0000-0003-4537-6143)
- Ibrahim N. Muhsen (ORCID: https://orcid.org/0000-0002-7156-2532)
- Vamsi Kota (ORCID: https://orcid.org/0000-0002-5290-9289)
- Caitlin Guzowski
- Veronika Bachanová (ORCID: https://orcid.org/0000-0002-9325-432X)
- Sang‐Bing Tsai (ORCID: https://orcid.org/0000-0001-6988-5829)
- Talal Hilal (ORCID: https://orcid.org/0000-0001-8249-4128)
- Chenyu Lin (ORCID: https://orcid.org/0000-0002-4542-4232)
- Aaron C. Logan (ORCID: https://orcid.org/0000-0002-1179-5879)
- Ryan D. Cassaday (ORCID: https://orcid.org/0000-0002-3424-2425)
- Minoo Battiwalla (ORCID: https://orcid.org/0000-0001-6440-1899)
- Sean Tracy (ORCID: https://orcid.org/0000-0001-7047-2589)
- Kaitlyn C. Dykes (ORCID: https://orcid.org/0000-0002-1638-1755)
- Abdullah Ladha (ORCID: https://orcid.org/0009-0006-9598-6467)
- Anjali S. Advani (ORCID: https://orcid.org/0000-0003-0015-5902)
- Kate Miller (ORCID: https://orcid.org/0000-0002-6582-8031)
- Yannis K. Valtis (ORCID: https://orcid.org/0000-0001-8927-8006)
- Noelle V. Frey (ORCID: https://orcid.org/0000-0003-3688-9836)
- Timothy E. O’Connor (ORCID: https://orcid.org/0000-0003-3249-807X)
- Michael R. Bishop (ORCID: https://orcid.org/0000-0002-3979-9273)
- Nikeshan Jeyakumar (ORCID: https://orcid.org/0000-0001-9979-4434)
- Amy Zhang (ORCID: https://orcid.org/0000-0002-9130-0660)
- Mohamed Ahmed (ORCID: https://orcid.org/0000-0002-0260-1921)
- Jae H. Park (ORCID: https://orcid.org/0000-0002-2903-5130)
- Ahmed Galal (ORCID: https://orcid.org/0000-0002-5962-5537)
- Shahbaz A. Malik (ORCID: https://orcid.org/0000-0001-9435-3285)
- Maryann Stefan
- Héctor Zambrano
- Katherine Sutherland
Institutions
- Northside Hospital (US)
- University of Southern California (US)
- Cedars-Sinai Medical Center (US)
- City Of Hope National Medical Center (US)
- University of Minnesota (US)
- Loyola University Medical Center (US)
- Memorial Sloan Kettering Cancer Center (US)
- University of California, Los Angeles (US)
- Oregon Health & Science University (US)
- Duke University (US)
- University of California, San Francisco (US)
- Baylor College of Medicine (US)
- University of Washington (US)
- University of Utah (US)
- University of Arkansas Medical Center (US)
- Huntsman Cancer Institute (US)
- University of Rochester Medical Center (US)
- Moffitt Cancer Center (US)
- University of California San Diego (US)
- University of Chicago (US)
- Augusta University Health (US)
- Sarah Cannon (US)
- Methodist Hospital (US)
- Dana-Farber Cancer Institute (US)
- Mayo Clinic Hospital (US)
- Stanford Blood Center (US)
- University of Colorado Anschutz Medical Campus (US)
- University of Pennsylvania (US)
- University of California, Davis (US)
- Vanderbilt University Medical Center (US)
- Stanford University (US)
Publication Details
- Journal
- Journal of Clinical Oncology
- Published
- 2024-10-17
- DOI
- https://doi.org/10.1200/jco.24.00321
- Citations
- 25
- Primary Topic
- CAR-T cell therapy research
- Type
- article
- Field-Weighted Citation Impact
- 7.06