E5-((3-phenoxyphenyl)diazenyl)quinolin-8-ol (PPDQ) : A Novel Promising Anticorrosive for Mild Steel in Acid Media, and a Pharmacologically Potent Antidiabetic, Antioxidant Azo Dye

A novel quinoline based azo dye 5-((3-phenoxyphenyl)diazenyl)quinolin-8-ol (PPDQ) was synthesized using conventional one pot MCR pathway and its structure has been confirmed by multinuclear (1H & 13C) and mass spectral techniques. PPDQ subjected for remarkable analytical applications like anticorrosion potential for mild steel in acidic media. Further, the experimental results were compared with that of the theoretical DFT based calculations and found to be in good agreement with each other. To evaluate the pharmacological activity of the compound invitro antidiabetic and antioxidant activity were carried out. The corrosion inhibition potential of the PPDQ was explored using electrochemical method which exhibited maximum corrosion inhibition efficiency up to 77% on mild steel in 1 M HCl media, further the anticorrosion potential was confirmed by quantum chemical calculations (DFT, ESP diagrams). Antidiabetic activity and antioxidant potency was evaluated using DPPH, and ABTS radical scavenging assay. Further, the in-vitro values were compared with insilico molecular docking studies.

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Publication Details

Journal
Orbital - The Electronic Journal of Chemistry
Published
2024-10-17
DOI
https://doi.org/10.17807/orbital.v16i3.21006
Primary Topic
Corrosion Behavior and Inhibition
Type
article
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article

E5-((3-phenoxyphenyl)diazenyl)quinolin-8-ol (PPDQ) : A Novel Promising Anticorrosive for Mild Steel in Acid Media, and a Pharmacologically Potent Antidiabetic, Antioxidant Azo Dye

K. S. Devaraju, K. Sunil, N.K. Lokanath, A.C. Kumbharkhane et al.
Orbital - The Electronic Journal of Chemistry
Corrosion Behavior and Inhibition
article

E5-((3-phenoxyphenyl)diazenyl)quinolin-8-ol (PPDQ) : A Novel Promising Anticorrosive for Mild Steel in Acid Media, and a Pharmacologically Potent Antidiabetic, Antioxidant Azo Dye

K. S. Devaraju, K. Sunil, N.K. Lokanath, A.C. Kumbharkhane, H Ramesh, Chandrashekar Chandrashekar K S, Narayana Hebbar N.
article en

Abstract

A novel quinoline based azo dye 5-((3-phenoxyphenyl)diazenyl)quinolin-8-ol (PPDQ) was synthesized using conventional one pot MCR pathway and its structure has been confirmed by multinuclear (1H & 13C) and mass spectral techniques. PPDQ subjected for remarkable analytical applications like anticorrosion potential for mild steel in acidic media. Further, the experimental results were compared with that of the theoretical DFT based calculations and found to be in good agreement with each other. To evaluate the pharmacological activity of the compound invitro antidiabetic and antioxidant activity were carried out. The corrosion inhibition potential of the PPDQ was explored using electrochemical method which exhibited maximum corrosion inhibition efficiency up to 77% on mild steel in 1 M HCl media, further the anticorrosion potential was confirmed by quantum chemical calculations (DFT, ESP diagrams). Antidiabetic activity and antioxidant potency was evaluated using DPPH, and ABTS radical scavenging assay. Further, the in-vitro values were compared with insilico molecular docking studies.

Orbital - The Electronic Journal of Chemistry
Karnatak University (IN), University of Mysore (IN), Shri Dharmasthala Manjunatheswara College of Ayurveda and Hospital (IN), Institute of Engineering (NP), Management Sciences (United States) (US)
Clean water and sanitation
Openalex Percentile: Top 89%
Corrosion Behavior and Inhibition
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E5-((3-phenoxyphenyl)diazenyl)quinolin-8-ol (PPDQ) : A Novel Promising Anticorrosive for Mild Steel in Acid Media, and a Pharmacologically Potent Antidiabetic, Antioxidant Azo Dye — K. S. Devaraju, K. Sunil, et al. · Orbital - The Electronic Journal of Chemistry (2024) | TGRS Research Map | TGRS