Mast cell MrgprB2 in neuroimmune interaction in IgE-mediated airway inflammation and its modulation by β-arrestin2
The data presented herein suggest that SP-mediated MrgprB2 activation contributes to AAI and goblet cell hyperplasia in mice. Furthermore, these responses are modulated by β-arr2, which promotes MC recruitment to facilitate their activation through FcεRI.
Authors
- Sangita Sutradhar
- Hydar Ali (ORCID: https://orcid.org/0000-0001-9190-1960)
Institutions
- University of Pennsylvania (US)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2024-10-17
- DOI
- https://doi.org/10.3389/fimmu.2024.1470016
- Citations
- 6
- Primary Topic
- Mast cells and histamine
- Type
- article
- Field-Weighted Citation Impact
- 1.44