Recovery from rituximab-associated persistent hypogammaglobulinaemia in children with nephrotic syndrome
A significant portion of patients with RTX-associated persistent hypogammaglobulinaemia did not exhibit recovery even after 1 year. Moreover, the data indicate that patients with a history of steroid-resistant NS have a significantly lower probability of recovering from this condition. Agranulocytosis under hypogammaglobulinaemia was significantly associated with an elevated risk of serious infections.
Authors
- Riku Hamada (ORCID: https://orcid.org/0000-0002-7151-459X)
- Toru Uchimura (ORCID: https://orcid.org/0009-0000-7057-2475)
- Takayuki Okamoto (ORCID: https://orcid.org/0000-0002-6029-451X)
- Hiroshi Tanaka (ORCID: https://orcid.org/0000-0001-7057-813X)
- Toshiyuki Ohta
- Takuo Kubota (ORCID: https://orcid.org/0000-0003-4483-4405)
- Shuichi Ito (ORCID: https://orcid.org/0000-0002-5242-8987)
- Takuya Fujimaru (ORCID: https://orcid.org/0000-0002-6825-3456)
- Aya Inaba
- Mayumi Sako
- Seiji Tanaka (ORCID: https://orcid.org/0000-0003-3882-3494)
- Daishi Hirano (ORCID: https://orcid.org/0000-0002-2398-5928)
- Koichi Kamei (ORCID: https://orcid.org/0000-0003-3528-6961)
Institutions
- Osaka Gakuin University (JP)
- Jikei University School of Medicine (JP)
- Hokkaido University (JP)
- Yokohama City University Medical Center (JP)
- St. Luke's International Hospital (JP)
- Kurume University Medical Center (JP)
- Hiroshima Prefectural Hospital (JP)
- National Center For Child Health and Development (JP)
- Tokyo Metropolitan Children's Medical Center (JP)
- Hirosaki University Hospital (JP)
- Yokohama City University (JP)
- The University of Osaka (JP)
Publication Details
- Journal
- Nephrology Dialysis Transplantation
- Published
- 2024-10-17
- DOI
- https://doi.org/10.1093/ndt/gfae228
- Citations
- 10
- Primary Topic
- Immunodeficiency and Autoimmune Disorders
- Type
- article
- Field-Weighted Citation Impact
- 2.40