“Dictionary of immune responses” reveals the critical role of monocytes and the core target IRF7 in intervertebral disc degeneration
These findings offer a multidimensional understanding of the pathogenesis of IDD, pinpointing monocytes and key genes as potential diagnostic and therapeutic targets. They provide novel insights into potential diagnostic and therapeutic targets for IDD.
Authors
- Xiaolong Chen (ORCID: https://orcid.org/0000-0002-1040-1655)
- Jianye Tan
- Xinxin Miao
- Jinghong Yuan (ORCID: https://orcid.org/0000-0002-5180-8646)
- Guanfeng Huang
- Xigao Cheng (ORCID: https://orcid.org/0000-0002-6105-1499)
- Chongzhi Pan (ORCID: https://orcid.org/0000-0003-1600-7779)
- Huajun Pan
- Dingwen He
- Kaihui Li (ORCID: https://orcid.org/0000-0003-3410-8995)
- Wei Xiong (ORCID: https://orcid.org/0000-0002-3017-9895)
- Jiangminghao Zhao
- Peichuan Xu
- Tao Li (ORCID: https://orcid.org/0000-0002-0675-5952)
Institutions
- Nanchang University (CN)
- Second Affiliated Hospital of Nanchang University (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2024-10-17
- DOI
- https://doi.org/10.3389/fimmu.2024.1465126
- Citations
- 2
- Primary Topic
- Spine and Intervertebral Disc Pathology
- Type
- article
- Field-Weighted Citation Impact
- 0.85
Funders
- Natural Science Foundation of Jiangxi Province