The clinical relevance of surgical specimens for RNA sequencing in lung cancer: a cohort study

Small samples obtained using nonsurgical procedures are suitable for NGS analysis in clinical practice. However, surgical sampling showed a relatively lower success rate for RNA sequencing than nonsurgical sampling. This information may help in the development of protocols to reduce RNA degradation during the surgical process.

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Publication Details

Journal
Frontiers in Oncology
Published
2024-10-18
DOI
https://doi.org/10.3389/fonc.2024.1462519
Primary Topic
Cancer Genomics and Diagnostics
Type
article
Field-Weighted Citation Impact
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article

The clinical relevance of surgical specimens for RNA sequencing in lung cancer: a cohort study

Jeongha Mok, Ahrong Kim, Jeong Su Cho, Kyungbin Kim et al.
Frontiers in Oncology
Cancer Genomics and Diagnostics
article

The clinical relevance of surgical specimens for RNA sequencing in lung cancer: a cohort study

Jeongha Mok, Ahrong Kim, Jeong Su Cho, Kyungbin Kim, Jung Seop Eom, Mi‐Hyun Kim, Hyo Yeong Ahn, Ju Sun Song, Soo Han Kim, Min Ki Lee
article en

Abstract

Small samples obtained using nonsurgical procedures are suitable for NGS analysis in clinical practice. However, surgical sampling showed a relatively lower success rate for RNA sequencing than nonsurgical sampling. This information may help in the development of protocols to reduce RNA degradation during the surgical process.

Frontiers in OncologyVol. 14
Green Cross (South Korea) (KR), Pusan National University Hospital (KR), Pusan National University (KR), Green Cross International (US)
Good health and well-being
Openalex Percentile: Top 73%
Cancer Genomics and Diagnostics
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