Evans syndrome: An uncommon hematological conundrum in a young adult: A case report

Evans syndrome is a rare autoimmune-mediated cytopenic disorder. We described the case of a male 27-year-old who had a 15-day history of fever, cough, and myalgia. Although the clinical examination other than a fever is unremarkable, blood workup and cytochemistry showed an autoimmune hemolytic reaction and peripheral destruction of platelets consistent with Evans syndrome. The patient was given multiple transfusions of RBC and platelets in addition to oral corticosteroids, parenteral folic acid, and vitamin B12. This case highlights the importance of considering Evans Syndrome in the differential diagnosis and timely management for a better patient outcome. The following prescriptions were given to the patient upon discharge: injectable deltacortil, tab folic acid, and Cap Opt-D. The patient was instructed to come see the outpatient department at the hospital. This case report highlights the uncharted region of Evans Syndrome in Pakistan. • Evans syndrome is a rare immune-mediated cytopenic illness. • Prompt recognition and treatment are crucial for improving prognosis. • Failure to timely investigate and treat can lead to lethal short and long-term effects.

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Publication Details

Journal
Medical Reports
Published
2024-10-17
DOI
https://doi.org/10.1016/j.hmedic.2024.100121
Primary Topic
Blood groups and transfusion
Type
article
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article

Evans syndrome: An uncommon hematological conundrum in a young adult: A case report

Faryal Afridi, Tooba Fida, Muhammad Fawad Ashraf, Hala Abdel Halim et al.
Medical Reports
Blood groups and transfusion
article

Evans syndrome: An uncommon hematological conundrum in a young adult: A case report

Faryal Afridi, Tooba Fida, Muhammad Fawad Ashraf, Hala Abdel Halim, Muhammad Usama bin Shabbir, Ishwa Ghouri
article en

Abstract

Evans syndrome is a rare autoimmune-mediated cytopenic disorder. We described the case of a male 27-year-old who had a 15-day history of fever, cough, and myalgia. Although the clinical examination other than a fever is unremarkable, blood workup and cytochemistry showed an autoimmune hemolytic reaction and peripheral destruction of platelets consistent with Evans syndrome. The patient was given multiple transfusions of RBC and platelets in addition to oral corticosteroids, parenteral folic acid, and vitamin B12. This case highlights the importance of considering Evans Syndrome in the differential diagnosis and timely management for a better patient outcome. The following prescriptions were given to the patient upon discharge: injectable deltacortil, tab folic acid, and Cap Opt-D. The patient was instructed to come see the outpatient department at the hospital. This case report highlights the uncharted region of Evans Syndrome in Pakistan. • Evans syndrome is a rare immune-mediated cytopenic illness. • Prompt recognition and treatment are crucial for improving prognosis. • Failure to timely investigate and treat can lead to lethal short and long-term effects.

Medical ReportsVol. 8
King Edward Medical University (PK), Pakistan Institute of Medical Sciences (PK), Ras al-Khaimah Medical and Health Sciences University (AE)
Openalex Percentile: Top 71%
Blood groups and transfusion
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Evans syndrome: An uncommon hematological conundrum in a young adult: A case report — Faryal Afridi, Tooba Fida, et al. · Medical Reports (2024) | TGRS Research Map | TGRS