Trial-Adjusted Versus Generic Simulated Comparator Trial (SCT) Settings for Selection Bias Appraisal Using the I2 Test
I<sup>2</sup> testing with trial-adjusted SCT settings increased the odds of identifying selection bias in clinical trials and did not significantly alter the odds in smaller trials with fewer than 200 patients per intervention group.
Authors
- Steffen Mickenautsch (ORCID: https://orcid.org/0000-0002-4994-2328)
- Veerasamy Yengopal (ORCID: https://orcid.org/0000-0003-4284-3367)
Institutions
- University of Cape Town (ZA)
- University of the Witwatersrand (ZA)
- University of the Western Cape (ZA)
Publication Details
- Journal
- Cureus
- Published
- 2024-10-16
- DOI
- https://doi.org/10.7759/cureus.71668
- Citations
- 2
- Primary Topic
- Statistical Methods in Clinical Trials
- Type
- article
- Field-Weighted Citation Impact
- 1.42