Anti-inflammatory Potential of Costus speciosus rhizome BioactivePhytochemicals: A Combined GC-MS and Computational ApproachTargeting TLR-4 Signaling
These findings highlight the therapeutic potential of <i>Costus speciosus</i> phytocompounds, particularly compound 7, as potent anti-inflammatory modulators. Further research is warranted to validate their anti-inflammatory and neuroprotective effects in pre-clinical models, paving the way for their development as novel therapeutic agents for inflammatory diseases.
Authors
- Sourav Santra
- Subhrajeet Sahoo
- A. Nirmal Paul Raj
- Sivaraman Jayanthi (ORCID: https://orcid.org/0000-0001-6722-1658)
- Vimala Raghavan
- Karthikeyan Ramesh
- Siva Sankar Sana (ORCID: https://orcid.org/0000-0003-1988-6772)
- Arghya Chakravorty (ORCID: https://orcid.org/0000-0002-7522-8304)
- Sahil Luktuke
- Sudip Das (ORCID: https://orcid.org/0000-0002-5137-4796)
- Arabinda Samanta (ORCID: https://orcid.org/0000-0001-6720-1390)
Institutions
- Vidyasagar University (IN)
- Yeungnam University (KR)
- Jawaharlal Institute of Post Graduate Medical Education and Research (IN)
- Vellore Institute of Technology University (IN)
Publication Details
- Journal
- Current Computer - Aided Drug Design
- Published
- 2024-10-17
- DOI
- https://doi.org/10.2174/0115734099309926241007055607
- Primary Topic
- Pharmacological Effects of Medicinal Plants
- Type
- article
- Field-Weighted Citation Impact
- 0.00