Candida Albicans Candidalysin ECE1 Gene − A Potent Virulence Factor for Oral Squamous Cell Carcinoma and Oral Potentially Malignant Disorders

The results suggest the significant role of candidalysin in oral oncogenesis. The high odds and risk ratio specify a strong association between candidalysin and these conditions. Screening this gene in a large number of isolates would further reinforce their role in oncogenesis. Future studies in characterizing their virulence on normal cell lines would clarify the importance of candidalysin in promoting oncogenesis.