Does Serum Delta FSH Level Provided with High Starting Dose FSH Differ Among Various Ovarian Responses?

The objective of this study is to evaluate whether serum delta FSH levels (the percentage difference of serum FSH between antagonist starting day and basal serum FSH level) differ between patients with different COH responses (poor, suboptimal response and normoresponders) who stimulated with a high (300 IU) fixed recombinant FSH dose during flexible antagonist cycles. This study is a retrospective cross sectional cohort study conducted in a tertiary ART Center. 122 women were evaluated, of which, 51 were poor responders, 52 had suboptimal response and 19 had normal response. The primary outcome is to evaluate the spot serum FSH levels on the first day of GnRH antagonist dose administration and the delta FSH levels between groups. Basal serum FSH levels differed significantly between (7[5.2-8.6], 5.7[4.6-7.2], 4.8[4.1-5.3] poor, suboptimal and normoresponders respectively; p